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Juan Martin Del Potro wins Mercedes Cup - Photos WTA Womens Tennis *******tenniswta.blogspot**** ATP Mens Tennis *******tennis-atp.blogspot**** Watch Sports Online *******watch-freesportsonline.blogspot****/ Juan martin del Potro *******juanmartindelpotro.blopgspot****
28 Jul 2008
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to watch on yr mac or pc - *******tennis.trueonlinetv****/?Watch-Tennis-Live-618 - to watch on yr handheld (pda) or mobile - *******www.truemedia.mobi/?ATP-Tennis-Live-618 - -(-tgs) bnp paribas Open, indian Wells, , live streaming of tennis , atp bnp paribas Open, , bnp paribas Open, tickets , bnp paribas Open, indian Wells, 2012 , bnp paribas Open, 2012 schedule , bnp paribas Open, 2012 tickets , indian Wells, wta , indian Wells, wta 2012 , wta indian Wells, live , wta tennis indian Wells, , stream live tennis , indian Wells, tennis wta , wta indian Wells, live stream , stream live tennis , , live tennis stream , stream tennis live , tennis live for free ,
18 Mar 2012
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Celebrate Rafael Nadal's rise to World No. 1 in the South African Airways ATP World Rankings in this tribute clip.
18 Dec 2008
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6:03
MX2 Pilot Thrills Audiences Nationwide Airshow pilot Rob Holland's bio boasts that he has "never known a time where he was not completely obsessed with Aviation and Aerobatics. At a young age his Dad brought him to an airshow where he saw an airplane flying upside down, and knew that was what he HAD to do." It's an age-old story... boy/girl sees planes, boy/girl falls in love with planes, boy/girl becomes an airshow pilot. Holland is proof that this age-old formula is alive and well... and thriving in his home-state of New Hampshire. He notes that he has been flying now since the age of 18 and has accumulated greater than 8500 hours of flight time in over 156 different types of aircraft ranging from Piper Cubs to Regional Transport Aircraft, gliders to high performance aerobatic machines. Rated as an ATP with CFI, CFII, IGI, AGI ratings, Rob also holds a glider rating. It's also been a diverse aviation career so far: flight instructor, banner tow pilot, aircraft ferry pilot, Pilatus PC-12 corporate pilot, and commuter airline pilot. He currently works full time both domestically and abroad as an professional airshow pilot and an aerobatic flight instructor. His aerobatic bona fides are equally impressive. In 2008 Rob Holland became the World Advanced Aerobatic Champion and helped pave the way for team USA to earn the Gold at the 8th World Advanced Aerobatic Championships. Rob is a three-time member of the United States Advanced Aerobatic Team. He was the top placing American at the 2004, 2006 and 2008 Advanced World Aerobatic Championships (AWAC). Rob placed second over all in the world at the 2006 AWAC held in Radom, Poland and helped the US Aerobatic Team secure second place in the team standings. Rob Holland is also the 2008 US National Unlimited Freestyle Champion. Rob has a Level One Unrestricted Aerobatic Waiver for airshows. "Solo Aerobatics", "Formation Aerobatics", "Circle Jumpers", and "Wing Walking Pilot," along with numerous aircraft types, are authorized on his Low Level Aerobatic Waiver. Rob was voted to the Board of Directors of the International Aerobatic Club in 2006. Rob flies an MX2 monoplane, built by MX Aircraft of North Carolina. The MX2 is a 385+ horsepower brute powered by a Lycoming AEIO-540 Aerobatic Engine, and boasts a structural profile that can pull G-loads of plus/minus 16 G’s. Holland boasts that this means, "tighter turns and loops and a whole variety of maneuvers that will redefine the word 'aerobatic'." The MX2 rolls at a breath-taking 400+ degrees per second and is constructed entirely of pre-impregnated epoxy carbon fiber composite material. Aero-TV Checks Out Some Unusual Attitudes With Airshow Pilot Rob Holland! FMI: www.ultimateairshows****, www.mxaircraft****, www.aero-tv****, www.youtube****/aerotvnetwork, *******twitter****/AeroNews Copyright 2009, Aero-News Network, Inc., ALL Rights Reserved.
18 Mar 2009
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9:37
Aspen Avionics' Evolution EFIS Now Approved In Nearly 400 Aircraft Models It's been a whirlwind year for the folks of Aspen Avionics. Just a few weeks ago, Aspen received its Approved Model List Supplemental Type Certificate (AML-STC) for the EFD1000 Primary Flight Display (PFD), from the almighty FAA. This certification -- combined with the TSO (Technical Standard Order) certification granted to the company two weeks ago, as ANN reported -- authorizes installation of Aspen’s Evolution PFD in almost 400 airplane makes and models. Coming before the end of March 2008, the AML-STC enabled Aspen Avionics to start shipping, and its dealers to start installing, Evolution Flight Display systems... on track with the schedule Aspen promised to its customers. Announced last year at Oshkosh, Aspen bills its Evolution Flight Display system is an affordable glass cockpit solution for general aviation aircraft. With prices starting under $6,000, the modular and upgradeable Evolution system breaks the price barrier and makes the safety benefits of the most advanced glass cockpit technologies finally accessible to the vast majority of the GA aircraft fleet. Certification of the Evolution Flight Display is the second TSO Aspen Avionics has received. The company’s innovative AT300 Hazard Awareness Display received certification in November 2005. The certification process for the EFD1000 PFD took approximately 18 months to complete. With certification of its Evolution EFD1000 PFD under their belt, the crew at Aspen Avionics looks forward to showing off their upcoming line of Evolution multi-function displays. Built upon the same certified hardwire platform as the PFDs, Aspen's MFD line adds additional situational awareness tools... while also providing a fully redundant backup to the PFD. The EFD1000 MFD and PFD combine high-resolution, sectional-style moving maps with dedicated and overlaid hazard awareness displays -- including weather, traffic and terrain advisories and warnings. The EFD1000 MFD also adds a second, independent air data, attitude and heading reference (ADAHRS) system for full redundancy. Aspen also gave hints to its next variant of the EFD1000 PFD, the ATP. Due in the second half of 2009, the ATP will add many MFD features, including sectional-style moving maps and integrated hazard awareness interfaces, to the PFD navigation display. It's an exciting time for the avionics biz... Let's Get Updated On Aspen Avionics With ANN's Aero-TV! FMI: www.aspenavionics**** Copyright 2008, Aero-News Network, Inc., ALL Rights Reserved.
14 May 2008
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3:00
Get $1500 fast payday loan in 24hr at *******samedaypaydayloans***.nr - Awesome! Roger Federer became the first tennis player to win the Qatar Open three times as he ended the reign of Nikolay Davydenko in Saturday's final. The world no. 2 was beaten by his Russian opponent in last year's semifinals, but avenged that result with a 6-3 6-4 win as he claimed the 67th ATP Tour title of his illustrious career. The Swiss star followed up his 2005 and 2006 triumphs to give himself a boost ahead of his Australian Open title defense in the opening grand slam of 2011 later this month. "I have had a good week. I really appreciate the support I get here. I have had good preparation. I can't believe that I am on the board already this year," Federer told reporters.
10 Jan 2011
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7:49
Among the other problems with the origin of even a single functional protein, Dr. Thaxton discusses the problem that specific sequences of Amino Acids (i.e. correct information) presents for 'natural' protein formation. Entire video may be viewed here: On The Origin Of Life - Thaxton *******www.youtube****/watch?v=6Ye3oDDAxeE Further resources: On The Origin Of Life And God - Henry F. Schaefer, III PhD. - video *******www.metacafe****/watch/4018204 Origin Of Life? - Probability Of Protein And The Information Of DNA - Dean Kenyon - video *******www.youtube****/watch?v=9VhR2BHhxeo In fact Dean Kenyon, who was a leading Origin Of Life researcher as well as a college textbook author on the subject, admitted after years of extensive research: "We have not the slightest chance for the chemical evolutionary origin of even the simplest of cells". Stephen C. Meyer - The Scientific Basis For the Intelligent Design Inference - video *******www.metacafe****/watch/4104651 Stephen Meyer - Functional Proteins And Information For Body Plans - video *******www.metacafe****/watch/4050681 Evolution vs. Functional Proteins - Doug Axe - Video *******www.metacafe****/watch/4018222 Estimating the prevalence of protein sequences adopting functional enzyme folds: Doug Axe: Excerpt: Starting with a weakly functional sequence carrying this signature, clusters of ten side-chains within the fold are replaced randomly, within the boundaries of the signature, and tested for function. The prevalence of low-level function in four such experiments indicates that roughly one in 10^64 signature-consistent sequences forms a working domain. Combined with the estimated prevalence of plausible hydropathic patterns (for any fold) and of relevant folds for particular functions, this implies the overall prevalence of sequences performing a specific function by any domain-sized fold may be as low as 1 in 10^77, adding to the body of evidence that functional folds require highly extraordinary sequences. *******www.ncbi.nlm.nih.gov/pubmed/15321723 Evolution's Fatal Flaw - The Origin Of Life - Chris Ashcraft PhD - video *******www.metacafe****/watch/4347153 The problem of 'left handed' homochirality found in the Miller-Urey experiment is of no small concern to any Origin Of Life scenario put forth by evolutionists: Dr. Charles Garner on the problem of Chirality in nature and Origin of Life Research - audio *******intelligentdesign.podomatic****/player/web/2010-04-12T17_21_16-07_00 Homochirality and Darwin - Robert Sheldon - April 2010 Excerpt: there is no abiotic path from a racemic solution to a stereo-active solution of amino acid(s) that doesn't involve a biotic chiral agent, be it chiral beads or Louis Pasteur himself. Like many critiques of ID, the problem with these "Darwinist" solutions is that they always smuggle in some information, in this case, chiral agents. *******procrustes.blogtownhall****/2010/04/27/homochirality_and_darwin.thtml Homochirality and Darwin: part 2 - Robert Sheldon - May 2010 Excerpt: With regard to the deniers who think homochirality is not much of a problem, I only ask whether a solution requiring multiple massive magnetized black-hole supernovae doesn't imply there is at least a small difficulty to overcome? A difficulty, perhaps, that points to the non-random nature of life in the cosmos? *******procrustes.blogtownhall****/2010/05/21/homochirality_and_darwin_part_2.thtml The severity of the homochirality problem begins to highlight the number one question facing any Origin Of Life research. Namely, "Where is the specified complexity (information) coming from?" Even this recent 'evolution friendly' article readily admitted the staggering level of 'specified complexity' (information) being dealt with in the first cell: Was our oldest ancestor a proton-powered rock? - Oct. 2009 Excerpt: “There is no doubt that the progenitor of all life on Earth, the common ancestor, possessed DNA, RNA and proteins, a universal genetic code, ribosomes (the protein-building factories), ATP and a proton-powered enzyme for making ATP. The detailed mechanisms for reading off DNA and converting genes into proteins were also in place. In short, then, the last common ancestor of all life looks pretty much like a modern cell.” *******www.newscientist****/article/mg20427306.200-was-our-oldest-ancestor-a-protonpowered-rock.html I think David Abel, the director of the Gene Emergence Project, does a very good job of highlighting just how crucial accounting for specified 'logical' information is to Origin of Life research: Chance and necessity do not explain the origin of life: Trevors JT, Abel DL. Excerpt: Minimal metabolism would be needed for cells to be capable of growth and division. All known metabolism is cybernetic--that is, it is programmatically and algorithmically organized and controlled. *******www.ncbi.nlm.nih.gov/pubmed/15563395 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/2009/10/intelligent-design-anthropic-hypothesis_19.html
20 Sep 2010
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0:31
Online streaming - *******tinyurl****/1March-24th-SonyEricsson-Open - live Tennis results on mobile - - *******tinyurl****/2-March-24th-Miami-Open-Mobile - Feliciano Lopez vs Richard Berankis live online - Jeremy Chardy vs Kei Nishikori tv link - Feliciano Lopez vs Richard Berankis live online - Andreas Seppi vs Mischa Zverev live tv link - watch Teymuraz Gabashvili vs Daniel Brand free tennis match - watch live Carlos Berlocq vs Jack Sock - Adrian Mannarino vs Ruben Ramirez Hidalgo online tennis match - Fabio Fognini vs Radek Stepanek - Sergiy Stakhovsky vs Grigor Dimitrov live - Blaz Kavcic vs Olivier Rochus webcast - Pere Riba vs Yen-Hsun Lu live tennis link - Philipp Petzschner vs Florent Serra live online - Janko Tipsarevic vs Robin Haase tv link - Ryan Harrison vs Rainer Schuettler live online - watch Frederico Gil vs Paul Capdeville free tennis match - watch live Florian Mayer vs Ivo Karlovic - Pablo Cuevas vs Michael Berrer live tv link - March 24th, 2011 Miami Tennis Masters Series - ATP World Tour March 24th, 2011 Online - Feliciano Lopez vs Richard Berankis live online - March 24th, 2011 Miami Tennis Masters Series - ATP World Tour March 24th, 2011 Online - - tennis.trueonlinetv
24 Mar 2011
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4:58
related footnotes on Dr. Axe’s work: Nothing In Molecular Biology Is Gradual – Doug Axe PhD. – video Quote – “Charles Darwin said (paraphrase), ‘If anyone could find anything that could not be had through a number of slight, successive, modifications, my theory would absolutely break down.’ Well that condition has been met time and time again. Basically every gene, every protein fold. There is nothing of significance that we can show that can be had in a gradualist way. It’s a mirage. None of it happens that way. – Doug Axe PhD. *******www.metacafe****/watch/5347797/ Estimating the prevalence of protein sequences adopting functional enzyme folds: Doug Axe: 2004 Excerpt: The prevalence of low-level function in four such experiments indicates that roughly one in 10^64 signature-consistent sequences forms a working domain. Combined with the estimated prevalence of plausible hydropathic patterns (for any fold) and of relevant folds for particular functions, this implies the overall prevalence of sequences performing a specific function by any domain-sized fold may be as low as 1 in 10^77, adding to the body of evidence that functional folds require highly extraordinary sequences. *******www.ncbi.nlm.nih.gov/pubmed/15321723 Doug Axe Knows His Work Better Than Steve Matheson Excerpt: Regardless of how the trials are performed, the answer ends up being at least half of the total number of password possibilities, which is the staggering figure of 10^77 (written out as 100, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000, 000). Armed with this calculation, you should be very confident in your skepticism, because a 1 in 10^77 chance of success is, for all practical purposes, no chance of success. My experimentally based estimate of the rarity of functional proteins produced that same figure, making these likewise apparently beyond the reach of chance. *******www.evolutionnews****/2010/06/doug_axe_knows_his_work_better035561.html The Case Against a Darwinian Origin of Protein Folds – Douglas Axe – 2010 Excerpt Pg. 11: “Based on analysis of the genomes of 447 bacterial species, the projected number of different domain structures per species averages 991. Comparing this to the number of pathways by which metabolic processes are carried out, which is around 263 for E. coli, provides a rough figure of three or four new domain folds being needed, on average, for every new metabolic pathway. In order to accomplish this successfully, an evolutionary search would need to be capable of locating sequences that amount to anything from one in 10^159 to one in 10^308 possibilities, something the neo-Darwinian model falls short of by a very wide margin.” *******bio-complexity****/ojs/index.php/main/article/view/BIO-C.2010.1 Not only are functional proteins found to be extremely rare, thus undermining Darwinian presuppositions, but, as Dr. Axe pointed out in the OP video, the transition of any existent functional protein to a protein of a different function, by unguided Darwinian processes, is found to be of extreme, prohibitive, difficulty as well. The Evolutionary Accessibility of New Enzyme Functions: A Case Study from the Biotin Pathway – Ann K. Gauger and Douglas D. Axe – April 2011 Excerpt: We infer from the mutants examined that successful functional conversion would in this case require seven or more nucleotide substitutions. But evolutionary innovations requiring that many changes would be extraordinarily rare, becoming probable only on timescales much longer than the age of life on earth. *******bio-complexity****/ojs/index.php/main/article/view/BIO-C.2011.1/BIO-C.2011.1 When Theory and Experiment Collide — April 16th, 2011 by Douglas Axe Excerpt: Based on our experimental observations and on calculations we made using a published population model [3], we estimated that Darwin’s mechanism would need a truly staggering amount of time—a trillion trillion years or more—to accomplish the seemingly subtle change in enzyme function that we studied. *******www.biologicinstitute****/post/18022460402/when-theory-and-experiment-collide “Biologist Douglas Axe on Evolution’s (non) Ability to Produce New (Protein) Functions ” – video Quote: It turns out once you get above the number six [changes in amino acids] — and even at lower numbers actually — but once you get above the number six you can pretty decisively rule out an evolutionary transition because it would take far more time than there is on planet Earth and larger populations than there are on planet Earth. *******intelligentdesign.podomatic****/entry/2012-10-15T16_05_14-07_00 The Real Barrier to Unguided Human Evolution – Dr. Ann Gauger – April 25, 2012 Excerpt: Their results? They calculated it would take six million years for a single base change to match the target and spread throughout the population, and 216 million years to get both base changes necessary to complete the eight base binding site. Note that the entire time span for our evolution from the last common ancestor with chimps is estimated to be about six million years. Time enough for one mutation to occur and be fixed, by their account. To be sure, they did say that since there are some 20,000 genes that could be evolving simultaneously, the problem is not impossible. But they overlooked this point. Mutations occur at random and most of the time independently, but their effects are not independent. (Random) Mutations that benefit one trait (are shown to) inhibit another (Negative Epistasis; Lenski e-coli after 50,000 generations). *******www.evolutionnews****/2012/04/the_real_barrie058951.html More from Dr. Ann Gauger on why humans didn’t happen the way Darwin said – July 2012 Excerpt: Each of these new features probably required multiple mutations. Getting a feature that requires six neutral mutations is the limit of what bacteria can produce. For primates (e.g., monkeys, apes and humans) the limit is much more severe. Because of much smaller effective population sizes (an estimated ten thousand for humans instead of a billion for bacteria) and longer generation times (fifteen to twenty years per generation for humans vs. a thousand generations per year for bacteria), it would take a very long time for even a single beneficial mutation to appear and become fixed in a human population. You don’t have to take my word for it. In 2007, Durrett and Schmidt estimated in the journal Genetics that for a single mutation to occur in a nucleotide-binding site and be fixed in a primate lineage would require a waiting time of six million years. The same authors later estimated it would take 216 million years for the binding site to acquire two mutations, if the first mutation was neutral in its effect. Facing Facts But six million years is the entire time allotted for the transition from our last common ancestor with chimps to us according to the standard evolutionary timescale. Two hundred and sixteen million years takes us back to the Triassic, when the very first mammals appeared. One or two mutations simply aren’t sufficient to produce the necessary changes— sixteen anatomical features—in the time available. At most, a new binding site might affect the regulation of one or two genes. *******www.uncommondescent****/intelligent-design/more-from-ann-gauger-on-why-humans-didnt-happen-the-way-darwin-said/ There is also very good, indeed overwhelming, evidence as to why we should expect such severe constraint on the ability of proteins to mutate, step by step, amino acid by amino acid, from one function to another different function. Proteins are shown to be ‘context dependent’, meaning that the entirety of the amino acid sequence of a protein domain is involved in a specific function and is not built up gradually. The following notes flesh this ‘context dependent’ characteristic of proteins out: Why Proteins Aren’t Easily Recombined, Part 2 – Dr. Ann Gauger - May 17, 2012 Excerpt: In other words, even if only 10% of non-matching residues were changed, the resulting hybrid enzyme no longer functioned. Why? Because the substitution of different amino acids into the existing protein structure destabilized the fold, even though those same amino acids worked well in another context. Thus, each protein’s amino acid sequence works as a whole to help generate a proper stable fold, in a context-dependent fashion. *******www.evolutionnews****/2012/05/why_proteins_ar_1059771.html As well, functional proteins have now been shown to have a ‘Cruise Control’ mechanism, along the entirety of a protein structure, which works to ‘self-correct’ the integrity of a entire protein structure from any random mutations imposed on it. Proteins with cruise control provide new perspective: 2008 “A mathematical analysis of the experiments showed that the proteins themselves acted to correct any imbalance imposed on them through artificial mutations and restored the chain to working order.” *******www.princeton.edu/main/news/archive/S22/60/95O56/ Cruise Control permeating the whole of the protein structure??? This is an absolutely fascinating discovery. The equations of calculus involved in achieving even a simple process control loop, such as a dynamic cruise control loop, are very complex. In fact it seems readily apparent to me that highly advanced mathematical information must somehow ‘transcendentally permeate’ along the entirety of a protein structure, in order to achieve such control of the overall protein structure. This fact gives us clear evidence that there is far more functional information permeating proteins than meets the eye than simple rarity of amino acid sequences reveals (Szostak). Moreover this ‘oneness’ of cruise control, within the protein structure, can only ‘rationally’ be achieved through quantum computation/entanglement principles, and is inexplicable to the reductive materialistic approach of neo-Darwinism! For a sample of the equations that must be dealt with, to ‘engineer’ even a simple process control loop like cruise control for a single protein, please see this following site: PID controller A proportional–integral–derivative controller (PID controller) is a generic control loop feedback mechanism (controller) widely used in industrial control systems. A PID controller attempts to correct the error between a measured process variable and a desired setpoint by calculating and then outputting a corrective action that can adjust the process accordingly and rapidly, to keep the error minimal. *******en.wikipedia****/wiki/PID_controller It is in realizing the staggering level of engineering that must be dealt with, i.e. ‘intelligently designed’ beforehand, in order to achieve ‘cruise control’ for each individual protein, along the entirety of the protein structure, that it becomes apparent that Axe’s 1 in 10^77 estimate for rarity of finding specific functional proteins within ‘sequence space’ is, in all likelihood, far, far too generous. In fact the probabilities over various ‘specific’ configurations of amino acids within sequence space, which have been one of the primary arguments against neo-Darwinism thus far, simply do not even apply, at all, since the ’cause’ for the ‘non-local quantum information effect’ within proteins does not even reside within the material particles in the first place (i.e. falsification of local realism; (Einstein, Bohr, Bell, Wheeler, Aspect, Zeilinger). The following footnotes are further corroborating evidence that ‘protein specific’ quantum information/entanglement resides along/within the entirety of a functional protein amino acid chain constraining the chain to a specific function: Coherent Intrachain energy migration at room temperature – Elisabetta Collini & Gregory Scholes – University of Toronto – Science, 323, (2009), pp. 369-73 Excerpt: The authors conducted an experiment to observe quantum coherence dynamics in relation to energy transfer. The experiment, conducted at room temperature, examined chain conformations, such as those found in the proteins of living cells. Neighbouring molecules along the backbone of a protein chain were seen to have coherent energy transfer. Where this happens quantum decoherence (the underlying tendency to loss of coherence due to interaction with the environment) is able to be resisted, and the evolution of the system remains entangled as a single quantum state. ********www.scimednet****/sapphire/main.php?url=/quantum-coherence-living-cells-and-protein/ Myosin Coherence Excerpt: Absorbance (and emission) of frequency specific radiation (e.g. photosynthesis, vision, [biophotons]..), conversion of chemical energy into mechanical motion (e.g. ATP cleavage) and single electron transfers through biological polymers (e.g. DNA or proteins) are all quantum mechanical effects. *******www.energetic-medicine****/bioenergetic-articles/articles/63/1/Myosin-Coherence/Page1.html Cellular Communication through Light Excerpt: Information transfer is a life principle. On a cellular level we generally assume that molecules are carriers of information, yet there is evidence for non-molecular information transfer due to endogenous coherent light. This light is ultra-weak, is emitted by many organisms, including humans and is conventionally described as biophoton emission. *******www.plosone****/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005086 The mechanism and properties of bio-photon emission and absorption in protein molecules in living systems – May 2012 Excerpt: From the energy spectra, it was determined that the protein molecules could both radiate and absorb bio-photons with wavelengths of <3??m and 5–7??m, consistent with the energy level transitions of the excitons.,,, *******jap.aip****/resource/1/japiau/v111/i9/p093519_s1?isAuthorized=no Physicists Discover Quantum Law of Protein Folding – February 22, 2011 Quantum mechanics finally explains why protein folding depends on temperature in such a strange way. Excerpt: First, a little background on protein folding. Proteins are long chains of amino acids that become biologically active only when they fold into specific, highly complex shapes. The puzzle is how proteins do this so quickly when they have so many possible configurations to choose from. To put this in perspective, a relatively small protein of only 100 amino acids can take some 10^100 different configurations. If it tried these shapes at the rate of 100 billion a second, it would take longer than the age of the universe to find the correct one. Just how these molecules do the job in nanoseconds, nobody knows.,,, Their astonishing result is that this quantum transition model fits the folding curves of 15 different proteins and even explains the difference in folding and unfolding rates of the same proteins. That's a significant breakthrough. Luo and Lo's equations amount to the first universal laws of protein folding. That’s the equivalent in biology to something like the thermodynamic laws in physics. *******www.technologyreview****/view/423087/physicists-discover-quantum-law-of-protein/ As to the ‘minor problem' of protein folding itself: “Blue Gene’s final product, due in four or five years, will be able to “fold” a protein made of 300 amino acids, but that job will take an entire year of full-time computing.” Paul Horn, senior vice president of IBM research, September 21, 2000 *******www.news****/2100-1001-233954.html Networking a few hundred thousand computers together has reduced the time to a few weeks for simulating the folding of a single protein molecule: A Few Hundred Thousand Computers vs. A Single Protein Molecule – video *******www.metacafe****/watch/4018233 Not only are amino acid sequences of proteins shown to be ‘context dependent’ on the specific function of the protein, but, it turns out, that the function of the protein itself, in many cases, is context dependent on the specific function of the cell that a protein may be residing in: The Complexity of Gene Expression, Protein Interaction, and Cell Differentiation – Jill Adams, Ph.D. – 2008 Excerpt: it seems that a single protein can have dozens, if not hundreds, of different interactions,,, In a commentary that accompanied Stumpf’s article, Luis Nunes Amaral (2008) wrote, “These numbers provide a sobering view of where we stand in our cataloging of the human interactome. At present, we have identified less than 0.3% of all estimated interactions among human proteins. We are indeed at the dawn of systems biology.” *******www.nature****/scitable/topicpage/the-complexity-of-gene-expression-protein-interaction-34575 Human Genes: Alternative Splicing Far More Common Than Thought: – 2008 Excerpt: two different forms of the same protein, known as isoforms, can have different, even completely opposite functions. For example, one protein may activate cell death pathways while its close relative promotes cell survival. *******www.sciencedaily****/releases/2008/11/081102134623.htm Simplest Microbes More Complex than Thought – Dec. 2009 Excerpt: PhysOrg reported that a species of Mycoplasma,, “The bacteria appeared to be assembled in a far more complex way than had been thought.” Many molecules were found to have multiple functions: for instance, some enzymes could catalyze unrelated reactions, and some proteins were involved in multiple protein complexes.” *******www.creationsafaris****/crev200912.htm#20091229a Insight into cells could lead to new approach to medicines – 2010 Excerpt: Scientists expected to find simple links between individual proteins but were surprised to find that proteins were inter-connected in a complex web. Dr Victor Neduva, of the University of Edinburgh, who took part in the study, said: “Our studies have revealed an intricate network of proteins within cells that is much more complex than we previously thought. *******www.physorg****/news196402353.html Supplemental notes: Wheel of Fortune: New Work by Thornton’s Group Supports Time-Asymmetric Dollo’s Law – Michael Behe – October 5, 2011 Excerpt: Darwinian selection will fit a protein to its current task as tightly as it can. In the process, it makes it extremely difficult to adapt to a new task or revert to an old task by random mutation plus selection. *******www.evolutionnews****/2011/10/wheel_of_fortune_new_work_by_t051621.html Stability effects of mutations and protein evolvability. October 2009 Excerpt: The accepted paradigm that proteins can tolerate nearly any amino acid substitution has been replaced by the view that the deleterious effects of mutations, and especially their tendency to undermine the thermodynamic and kinetic stability of protein, is a major constraint on protein evolvability,, *******www.ncbi.nlm.nih.gov/pubmed/19765975 Corticosteroid Receptors in Vertebrates: Luck or Design? – Ann Gauger – October 11, 2011 Excerpt: if merely changing binding preferences is hard, even when you start with the right ancestral form, then converting an enzyme to a new function is completely beyond the reach of unguided evolution, no matter where you start. *******www.evolutionnews****/2011/10/luck_or_design051801.html “Mutations are rare phenomena, and a simultaneous change of even two amino acid residues in one protein is totally unlikely. One could think, for instance, that by constantly changing amino acids one by one, it will eventually be possible to change the entire sequence substantially… These minor changes, however, are bound to eventually result in a situation in which the enzyme has ceased to perform its previous function but has not yet begun its ‘new duties’. It is at this point it will be destroyed” Maxim D. Frank-Kamenetski, Unraveling DNA, 1997, p. 72. (Professor at Brown U. Center for Advanced Biotechnology and Biomedical Engineering) “A problem with the evolution of proteins having new shapes is that proteins are highly constrained, and producing a functional protein from a functional protein having a significantly different shape would typically require many mutations of the gene producing the protein. All the proteins produced during this transition would not be functional, that is, they would not be beneficial to the organism, or possibly they would still have their original function but not confer any advantage to the organism. It turns out that this scenario has severe mathematical problems that call the theory of evolution into question. Unless these problems can be overcome, the theory of evolution is in trouble.” Problems in Protein Evolution: Here are further notes that support the position that existing functional proteins are severely constrained in their ability to mutate step by step into new functions: Deciphering Design in the Genetic Code – Fazale Rana Excerpt: Sixty-four codons make up the genetic code. Because the genetic code only needs to encode 20 amino acids, some of the codons are redundant. That is, different codons code for the same amino acid. In fact, up to six different codons specify some amino acids. Others are specified by only one codon.,,, Genetic code rules incorporate a design that allows the cell to avoid the harmful effects of substitution mutations. For example, six codons encode the amino acid leucine (Leu). If at a particular amino acid position in a polypeptide, Leu is encoded by 5′ (pronounced five prime, a marker indicating the beginning of the codon). CUU, substitution mutations in the 3′ position from U to C, A, or G produce three new codons, 5′ CUC, 5′ CUA, and 5′ CUG, all of which code for Leu. The net effect produces no change in the amino acid sequence of the polypeptide. For this scenario, the cell successfully avoids the negative effects of a substitution mutation. Likewise, a change of C in the 5′ position to a U generates a new codon, 5′UUU, that specifies phenylalanine, an amino acid with similar physical and chemical properties to Leu. A change of C to an A or to a G produces codons that code for isoleucine and valine, respectively. These two amino acids also possess chemical and physical properties similar to leucine. Qualitatively, the genetic code appears constructed to minimize errors that result from substitution mutations.,,, The genetic code’s error-minimization properties are actually more dramatic than these results indicate. When researchers calculated the error-minimization capacity of one million randomly generated genetic codes, they discovered that the error-minimization values formed a distribution where the naturally occurring genetic code’s capacity occurred outside the distribution.18 Researchers estimate the existence of 10^18 possible genetic codes possessing the same type and degree of redundancy as the universal genetic code. All of these codes fall within the error-minimization distribution. This finding means that of 10^18 possible genetic codes, few, if any, have an error-minimization capacity that approaches the code found universally in nature. *******www.reasons****/articles/fyi-i.d.-in-dna-deciphering-design-in-the-genetic-code As well, the ‘errors/mutations’ that are found to occur in protein sequences are found to be ‘regulated errors’: Cells Defend Themselves from Viruses, Bacteria With Armor of Protein Errors – Nov. 2009 Excerpt: These “regulated errors” comprise a novel non-genetic mechanism by which cells can rapidly make important proteins more resistant to attack when stressed, *******www.sciencedaily****/releases/2009/11/091125134701.htm In fact there is little hope of a truly random (i.e. Darwinian) mutation ever making it through the gauntlet of the ribosome: The Ribosome: Perfectionist Protein-maker Trashes Errors Excerpt: The enzyme machine that translates a cell’s DNA code into the proteins of life is nothing if not an editorial perfectionist…the ribosome exerts far tighter quality control than anyone ever suspected over its precious protein products… To their further surprise, the ribosome lets go of error-laden proteins 10,000 times faster than it would normally release error-free proteins, a rate of destruction that Green says is “shocking” and reveals just how much of a stickler the ribosome is about high-fidelity protein synthesis.
16 Oct 2012
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5:05
Urgent Information!! Do YOU Think (Telme) is a Scam ? *******www.CreateAbundantSuccess**** Naeem Lewin Call Me!! 754-245-0193 (telme) (telme seviços de telefonia)( ºiran telme)(telme do brasil)(telme scam) (telme) (telme seviços de telefonia)( ºiran telme)(telme do brasil)(telme scam) (telme) (telme seviços de telefonia)( ºiran telme)(telme do brasil)(telme scam) YouTube – (Telme) 3gVideoCall Tutorial English Video tutorial explaining the usage of (Telme) 3gVideoCall ... YouTube - World WoIP2 (TelMe) WoIP2 Official Guide To touch the WoIP2 Technology is ... (Telme) Distributor Glynipher Co Blog(Telme) Evolution Project, which has introduced a new extraordinary phase for company's business, has been the undisputed protagonist of the event. ... All (Tel.Me.) phonesGSMArena****: (Tel.Me.) GSM cellphones. ... T910 • Tel.Me. T909c GSM 900 / 1800 129 x 44 x 18 mm T909c • (Tel.Me). T909 GSM 900 / 1800 109 x 44 x 22 mm T909 ... Cheap flights, flight tickets, bargain airfares, flight offersLooking for cheap flights? Then ATP, The Advanced Travel Partner has access to over 3 million airfares and special airfares with 63 airlines offering great .. telméclothing. (Telme)(Telme) Home Based Business Info at Npros****. (Telme) Overview, Product Info, and Rep Listings. (TelMe) Farebase BrochureLATEST NEWS; Jan 2008 - Saqib Ahmed has recently joined the (TelMe) Farebase team as Sales Director. Leads for (Telme)PreQualified Leads for (Telme) at Npros****. ... Visit the Npros**** classified section and promote your Telme business. Each of our classifieds get front ... TEL-ME-MOR -> Cooperation - Archive - TEL-ME-MORIf you are not redirectly automatically within five seconds, please click here. 7m3 ameriplan scam belgistan coastal vacations scam cyberwize scam ebay scam eroticon farebase groove theory hyip scam identity theft scam ketouba lisa sparxxx mlm scam motomco movistar network marketing scam phishing scam pips scam pyramid scam scam report survey scout scam surveyscout scam t919 tel me telme telme scam tsm100 tsm100v tsm30 ymmss scam
29 May 2008
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3:45
Veja como a ATP sintase usa o gradiente de hidrogênio para sintetizar ATP, a energia celular.
2 Sep 2010
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4:24
WTA Women's Tennis News - July 16th 2008 WTA Womens Tennis *******tenniswta.blogspot**** ATP Mens Tennis *******tennis-atp.blogspot**** Watch Sports Online *******watch-freesportsonline.blogspot****/
29 Jul 2008
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7:21
Directed by Yohei Saito. Taken from 'SEVEN IDIOTS' out on Erased Tapes -- April 22 (EU) 25 (UK) 26 (US), 2011. PRE-ORDER NOW: *******www.erasedtapes****/store/index/ERATP029 © 2011 Erased Tapes Records. All rights reserved. Official press release: World's End Girlfriend is a Japanese composer whose work blends complex sound structures with beautiful melodies, reaching from electronic glitch to jazz-infused rock to modern classical. Captivating, enthralling and like nothing you've heard before, WEG makes for a surprising yet central addition to London contemporary music label Erased Tapes. His brand new album 'SEVEN IDIOTS' will finally be released outside of Japan this April. Shifting seamlessly from catchy pop hooks to elaborate orchestrations and brutal IDM drones, it's an irregular pop album -- filled with twists and turns that will have you reaching for the repeat button. At first recorded with vocals, he took the unusual composing method of building up the songs before erasing all of their vocal parts. By dismantling and re-constructing each track, WEG has produced a genre-defying album that truly transcends categorisation. World's End Girlfriend hails from Nagasaki Kyushu, Japan and currently resides in Tokyo. Fascinated by his father's classical music collection, he began his foray into sound at the tender age of 10, creating his early compositions on keyboard, guitar, tape recorders and computers. To date he has composed more than 600 songs, for the most part unreleased testaments of his early experimentations. WEG first came on Europe's radar in 2002, invited to perform at Barcelona's renowned Sonar Festival. On the back of the collaborative album 'Palmless Prayer / Mass Murder Refrain' with Japanese post-rock band Mono, he embarked on extensive tours in Europe and North America in 2005, returning for an appearance at ATP Festival in 2008. Recently performing as a seven-piece ensemble, WEG's ostentious live show is currently selling out 800 capacity venues in Asia. Filmmakers seem smitten too, with the Go Shibata directed movie 'Late Bloomer' (2004) and the internationally renowned 'Air Doll' (2009) by award-winning director Hirokazu Koreeda both featuring soundtracks created by World's End Girlfriend. The music video for 'Les Enfants du Paradis', taken from 'SEVEN IDIOTS', has already received over 90.000 views on YouTube. Directed by Yohei Saito, this beguiling visual represents the high level of interest given to WEG's music, not widely available outside of Asia -- until now. 'The one album that would turn the entire music world on its head' (8.5/10) #6 Top 100 Releases -- The Silent Ballet (US) 'There are few artists who can make a human being as overjoyed, ardent, or terrified as Katsuhiko Maeda through the sheer art of music. ...there is no other conscientious artist in activity that crafts music in the same distinctive style as World's End Girlfriend' (8/10) -- PopMatters (US) 'A defining statement and a full-length that has more than realised his potential to be one of the most unique and vital solo artists in modern music' (9/10) -- Contact Music (UK) 'World's End Girlfriend sign to the label renowned for its recognition of innovative acts... and promises to blend sideways pop with strange and addictive hooks' -- Bearded Magazine (UK)
19 May 2011
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2:46
The latest update of sports news over Dhoni and Yuvraj being dropped for the Sri Lankan tour, Beijing preparing for 'green and safe' Olympics, Paes moving up eight places in ATP doubles rankings and much more. For more news, information, and updates log on to www.headlinesindia****.
16 Dec 2008
478
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6:11
Durch die Begegnung mit einem Lasertechniker entstand die Lasernadel-Akupunktur, eine Akupunktur mit Hilfe von Laserstrahlen. Durch den Kontakt mit russischen Forschungen wurde die intravense Laserblut-Bestrahlung entwickelt.Gerade bei Diabetes und Leberkrankheiten sind die russischen Forschungsergebnisse sensationell, die Dr. Weber mit Hilfe eines selbst entwickelten Gertes weitgehend besttigen kann. Diabetes-Patienten sterben heute blicherweise nicht mehr an ihrer Krankheit, denn Medikamente und Insulin machen das berleben mglich; aber die Nebenwirkungen sind zahlreich, und Herzinfarkt und Schlaganfall sind hufige Folgen der herkmmlichen Behandlung. Dr. Weber stellt Forschungsergebnisse von Dr. Wirz vor, der mit Hilfe des Gertes von Dr. Weber und einer speziellen Insulin-Frequenz 45 Diabetiker behandelt hat. Gewichtsreduktion, Cholesterinsenkung, Gewichtsreduktion, Beendigung von Schnarchen, Senkung des Augendrucks und andere positive (gesundheitliche) Folgen zeigt diese kleine Studie.Dr. Weber stellt auch die Ergebnisse einer Studie in Teheran mit kombinierter Laser-Therapie in der Kardiologie, Angiologie und Herzinsuffienz vor.Menschen mit chronischen Krankheiten, Diabetes, Krebs, BurnOut, usw. - alle diese Menschen leiden an Energiemangel. Durch gezielte Laserbehandlung kann die Produktion von ATP angeregt werden, womit dem Krper mehr Energie zur Verfgung gestellt wird.Im Sport wurde eine Leistungssteigerung bei Kraftsportlern um 12 % erzielt, im Ausdauersport zwischen 60 und 90 % - und all dies, ohne dass es als Doping gilt.Diese und andere interessante Videos erhalten Sie unter *******www.dvd-wissen****
3 Jul 2009
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1:45
Sean Bradley presents a live selection from Tennis Now magazine. This week: Top Ten Reasons Shirts Should Be Optional On The ATP Tour. Tough male tennis players, shirtless and sweaty. Visit www.TennisNow**** and subscribe for more every week.
19 Feb 2011
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