Results for: beneficial-mutations Search Results
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"I have seen estimates of the incidence of the ratio of deleterious-to-beneficial mutations which range from one in one thousand up to one in one million. The best estimates seem to be one in one million (Gerrish and Lenski, 1998). The actual rate of beneficial mutations is so extremely low as to thwart any actual measurement (Bataillon, 2000, Elena et al, 1998). Therefore, I cannot ...accurately represent how rare such beneficial mutations really are." (J.C. Sanford; Genetic Entropy page 24) - 2005 Estimation of spontaneous genome-wide mutation rate parameters: whither beneficial mutations? (Thomas Bataillon) Abstract......It is argued that, although most if not all mutations detected in mutation accumulation experiments are deleterious, the question of the rate of favourable mutations (and their effects) is still a matter for debate. *******www.nature****/hdy/journal/v84/n5/full/6887270a.html Distribution of fitness effects caused by random insertion mutations in Escherichia coli Excerpt: At least 80% of the mutations had a significant negative effect on fitness, whereas none of the mutations had a significant positive effect. *******www.springerlink****/content/r37w1hrq5l0q3832/ High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans ( Esther K. Davies, Andrew D. Peters, Peter D. Keightley) "In fitness assays, only about 4 percent of the deleterious mutations fixed in each line were detectable. The remaining 96 percent, though cryptic, are significant for mutation load...the presence of a large class of mildly deleterious mutations can never be ruled out. " *******www.sciencemag****/cgi/content/abstract/285/5434/1748 But in all the reading Ive done in the life-sciences literature, Ive never found a mutation that added information All point mutations that have been studied on the molecular level turn out to reduce the genetic information and not increase it. Lee Spetner - Ph.D. Physics - MIT - (Not By Chance: Shattering the Modern Theory of Evolution) "Bergman (2004) has studied the topic of beneficial mutations. Among other things, he did a simple literature search via Biological Abstracts and Medline. He found 453,732 mutation hits, but among these only 186 mentioned the word beneficial (about 4 in 10,000). When those 186 references were reviewed, almost all the presumed beneficial mutations were only beneficial in a very narrow sense- but each mutation consistently involved loss of function changes-hence loss of information. Sanford: Genetic Entropy Mutations, in summary, tend to induce sickness, death, or deficiencies. No evidence in the vast literature of heredity change shows unambiguous evidence that random mutation itself, even with geographical isolation of populations leads to speciation. Lynn Margulis - Acquiring Genomes [2003], p. 29. But there is no evidence that DNA mutations can provide the sorts of variation needed for evolution There is no evidence for beneficial mutations at the level of macroevolution, but there is also no evidence at the level of what is commonly regarded as microevolution. Jonathan Wells (PhD. - Molecular Biology) Evolution vs. Genetic Entropy - video *******www.youtube****/watch?v=mmbRbyv2PA0 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
27 May 2010
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Waiting Longer for Two Mutations, Part 5 - Michael Behe Excerpt: the appearance of a particular (beneficial) double mutation in humans would have an expected time of appearance of 216 million years, *******behe.uncommondescent****/2009/03/waiting-longer-for-two-mutations-part-5/ Simulating evolution by gene duplication of protein features that require multiple amino acid residues: Michael J. Behe and David W. Snoke Excerpt: We conclude that, in general, to be fixed in 10^8 generations, the production of novel protein features that require the participation of two or more amino acid residues simply by multiple point mutations in duplicated genes would entail population sizes of no less than 10^9.,,,The fact that very large population sizes—10^9 or greater—are required to build even a minimal [multi-residue] feature requiring two nucleotide alterations within 10^8 generations by the processes described in our model, and that enormous population sizes are required for more complex features or shorter times, seems to indicate that the mechanism of gene duplication and point mutation alone would be ineffective, at least for multicellular diploid species, because few multicellular species reach the required population sizes. *******www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2286568 "I have seen estimates of the incidence of the ratio of deleterious-to-beneficial mutations which range from one in one thousand up to one in one million. The best estimates seem to be one in one million (Gerrish and Lenski, 1998). The actual rate of beneficial mutations is so extremely low as to thwart any actual measurement (Bataillon, 2000, Elena et al, 1998). Therefore, I cannot ...accurately represent how rare such beneficial mutations really are." (J.C. Sanford; Genetic Entropy page 24) - 2005 Random Mutations Destroy Information - Perry Marshall - video *******www.metacafe****/watch/4023143/random_mutations_destroy_information_perry_marshall/ Mutation Studies, Videos, And Quotes *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjZjZnM5M21mZg Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
19 Feb 2010
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Richard Sternberg's website: *******www.richardsternberg****/ Waiting Longer for Two Mutations, Part 5 - Michael Behe Excerpt: the appearance of a particular (beneficial) double mutation in humans would have an expected time of appearance of 216 million years, *******behe.uncommondescent****/2009/03/waiting-longer-for-two-mutations-part-5/ Whale Evolution? - Exposing The Deception - video *******www.metacafe****/watch/4032568/whale_evolution_exposing_the_deception_in_the_fossil_record_dr_terry_mortenson/ Whale Tale Two Excerpt: We think that the most logical interpretation of the Pakicetus fossils are that they represent land-dwelling mammals that didn’t even have teeth or ears in common with modern whales. This actually pulls the whale evolution tree out by the roots. Evolutionists are back to the point of not having any clue as to how land mammals could possibly have evolved into whales. *******www.ridgecrest.ca.us/~do_while/sage/v6i2f.htm What Does It take To Change A Cow Into A Whale - David Berlinski - video *******www.youtube****/watch?v=DRqdvhL3pgM Chimpanzee? 10-10-2008 - Dr Richard Buggs - research geneticist at the University of Florida ...Therefore the total similarity of the genomes could be below 70%. *******www.refdag.nl/artikel/1366432/Chimpanzee.html Estimating the prevalence of protein sequences adopting functional enzyme folds: Doug Axe: Excerpt: Starting with a weakly functional sequence carrying this signature, clusters of ten side-chains within the fold are replaced randomly, within the boundaries of the signature, and tested for function. The prevalence of low-level function in four such experiments indicates that roughly one in 10^64 signature-consistent sequences forms a working domain. Combined with the estimated prevalence of plausible hydropathic patterns (for any fold) and of relevant folds for particular functions, this implies the overall prevalence of sequences performing a specific function by any domain-sized fold may be as low as 1 in 10^77, adding to the body of evidence that functional folds require highly extraordinary sequences. *******www.ncbi.nlm.nih.gov/pubmed/15321723 Evolution vs. Functional Proteins - Doug Axe - Video *******www.metacafe****/watch/4018222/evolution_vs_functional_proteins_where_did_the_information_come_from_doug_axe_stephen_meyer/ Chimps are not like humans - May 2004 Excerpt: the International Chimpanzee Chromosome 22 Consortium reports that 83% of chimpanzee chromosome 22 proteins are different from their human counterparts,,, The results reported this week showed that "83% of the genes have changed between the human and the chimpanzee—only 17% are identical—so that means that the impression that comes from the 1.2% [sequence] difference is [misleading]. In the case of protein structures, it has a big effect," Sakaki said. *******cmbi.bjmu.edu.cn/news/0405/119.htm Eighty percent of proteins are different between humans and chimpanzees; Gene; Volume 346, 14 February 2005: *******www.ncbi.nlm.nih.gov/pubmed/15716009 Stephen Meyer - Functional Proteins And Information For Body Plans - video *******www.metacafe****/watch/4050681/stephen_meyer_functional_proteins_and_information_for_body_plans/ The Paradox of the "Ancient" Bacterium Which Contains "Modern" Protein-Coding Genes: “Almost without exception, bacteria isolated from ancient material have proven to closely resemble modern bacteria at both morphological and molecular levels.” Heather Maughan*, C. William Birky Jr., Wayne L. Nicholson, William D. Rosenzweig§ and Russell H. Vreeland ; *******mbe.oxfordjournals****/cgi/content/full/19/9/1637 Mutation Studies, Videos, And Quotes *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjZjZnM5M21mZg Simulating evolution by gene duplication of protein features that require multiple amino acid residues: Michael J. Behe and David W. Snoke Excerpt: We conclude that, in general, to be fixed in 10^8 generations, the production of novel protein features that require the participation of two or more amino acid residues simply by multiple point mutations in duplicated genes would entail population sizes of no less than 10^9.,,,The fact that very large population sizes—10^9 or greater—are required to build even a minimal [multi-residue] feature requiring two nucleotide alterations within 10^8 generations by the processes described in our model, and that enormous population sizes are required for more complex features or shorter times, seems to indicate that the mechanism of gene duplication and point mutation alone would be ineffective, at least for multicellular diploid species, because few multicellular species reach the required population sizes. *******www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2286568 Evolution Cartoon - Waiting For That Beneficial Mutation - video *******www.youtube****/watch?v=71-QYtxi8Bw Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
3 May 2010
25377
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SIGNATURE IN THE CELL by Stephen C. Meyer *******www.signatureinthecell****/ Journey Inside The Cell - video *******www.youtube****/watch?v=1fiJupfbSpg Evolution vs. Functional Proteins - Doug Axe - Video *******www.youtube****/watch?v=M4FvdOxIDfU Estimating the prevalence of protein sequences adopting functional enzyme folds: Doug Axe: Excerpt: Combined with the estimated prevalence of plausible hydropathic patterns (for any fold) and of relevant folds for particular functions, this implies the overall prevalence of sequences performing a specific function by any domain-sized fold may be as low as 1 in 10^77, adding to the body of evidence that functional folds require highly extraordinary sequences. *******www.ncbi.nlm.nih.gov/pubmed/15321723 Refutation of Szostak's 1 in 10^12 functional protein paper: A Man-Made ATP-Binding Protein Evolved Independent of Nature Causes Abnormal Growth in Bacterial Cells Excerpt: "Recent advances in de novo protein evolution have made it possible to create synthetic proteins from unbiased libraries that fold into stable tertiary structures with predefined functions. However, it is not known whether such proteins will be functional when expressed inside living cells or how a host organism would respond to an encounter with a non-biological protein. Here, we examine the physiology and morphology of Escherichia coli cells engineered to express a synthetic ATP-binding protein evolved entirely from non-biological origins. We show that this man-made protein disrupts the normal energetic balance of the cell by altering the levels of intracellular ATP. This disruption cascades into a series of events that ultimately limit reproductive competency by inhibiting cell division." *******www.plosone****/article/info:doi%2F10.1371%2Fjournal.pone.0007385 Eighty percent of proteins are different between humans and chimpanzees; Gene; Volume 346, 14 February 2005: *******www.ncbi.nlm.nih.gov/pubmed/15716009 Yet by the late 1980s it was becoming obvious to most genetic researchers, including myself, since my own main research interest in the 80s and 90s was human genetics, that the heroic effort to find the information specifying lifes order in the genes had failed. There was no longer the slightest justification for believing that there exists anything in the genome remotely resembling a program capable of specifying in detail all the complex order of the phenotype (Body Plan)." Michael John Denton page 172 of Uncommon Dissent Waiting Longer for Two Mutations, Part 5 - Michael Behe Excerpt: the appearance of a particular (beneficial) double mutation in humans would have an expected time of appearance of 216 million years, *******behe.uncommondescent****/2009/03/waiting-longer-for-two-mutations-part-5/ Cortical Inheritance: The Crushing Critique Against Genetic Reductionism - Arthur Jones - video Part 1 *******www.youtube****/watch?v=5JzQ8ingdNY Part 2 *******www.youtube****/watch?v=o1bAX93zQ5o Darwin's Theory - Fruit Flies and Morphology - video *******www.youtube****/watch?v=hZJTIwRY0bs Evolution vs ATP Synthase - Molecular Machine - video *******www.youtube****/watch?v=qE3QJMI-ljc The Coding Found In DNA Surpasses Mans Ability to Code - Stephen Meyer - video *******www.youtube****/watch?v=HavmzWVt8IU Mathematically Defining Functional Information In Molecular Biology - Kirk Durston - video *******www.youtube****/watch?v=vUeCgTN7pOo The malaria parasite, and AIDS virus, due to their comparatively enormous population size, have in 1 year more mutation/duplication/selection events than all mammal lineages have had in the entire +100 million years they have been in the fossil record. What do we see? Michael Behe, The Edge of Evolution, pg. 162 Swine Flu, Viruses, and the Edge of Evolution "Indeed, the work on malaria and AIDS demonstrates that after all possible unintelligent processes in the cell--both ones we've discovered so far and ones we haven't--at best extremely limited benefit, since no such process was able to do much of anything. It's critical to notice that no artificial limitations were placed on the kinds of mutations or processes the microorganisms could undergo in nature. Nothing--neither point mutation, deletion, insertion, gene duplication, transposition, genome duplication, self-organization nor any other process yet undiscovered--was of much use." *******www.evolutionnews****/2009/05/swine_flu_viruses_and_the_edge.html Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
2 Jun 2010
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Natural Selection Reduces Genetic Information - Dr. Georgia Purdom - video *******www.youtube****/watch?v=izPzEgRtPKI Natural Selection Reduces Genetic Information - No Beneficial Mutations - Spetner - Denton - video *******www.youtube****/watch?v=OdZYguRuzn0 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
24 Jul 2011
1091
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6:49
Though Lenski claims the new citrate ability of E-Coli is proof of evolution, it is actually proof of Genetic Entropy. These following articles refute Lenski's supposed "evolution" of the citrate ability for the E-Coli bacteria after 20,000 generations of the E-Coli: Multiple Mutations Needed for E. Coli - Michael Behe Excerpt: As Lenski put it, “The only known barrier to aerobic growth on citrate is its inability to transport citrate under oxic conditions.” (1) Other workers (cited by Lenski) in the past several decades have also identified mutant E. coli that could use citrate as a food source. In one instance the mutation wasn’t tracked down. (2) In another instance a protein coded by a gene called citT, which normally transports citrate in the absence of oxygen, was overexpressed. (3) The overexpressed protein allowed E. coli to grow on citrate in the presence of oxygen. It seems likely that Lenski’s mutant will turn out to be either this gene or another of the bacterium’s citrate-using genes, tweaked a bit to allow it to transport citrate in the presence of oxygen. (He hasn’t yet tracked down the mutation.),,, If Lenski’s results are about the best we've seen evolution do, then there's no reason to believe evolution could produce many of the complex biological features we see in the cell. *******www.amazon****/gp/blog/post/PLNK3U696N278Z93O Lenski's e-coli - Analysis of Genetic Entropy Excerpt: Mutants of E. coli obtained after 20,000 generations at 37°C were less “fit” than the wild-type strain when cultivated at either 20°C or 42°C. Other E. coli mutants obtained after 20,000 generations in medium where glucose was their sole catabolite tended to lose the ability to catabolize other carbohydrates. Such a reduction can be beneficially selected only as long as the organism remains in that constant environment. Ultimately, the genetic effect of these mutations is a loss of a function useful for one type of environment as a trade-off for adaptation to a different environment. *******www.answersingenesis****/articles/aid/v4/n1/beneficial-mutations-in-bacteria Upon closer inspection, it seems Lenski's "cuddled" E. coli are actually headed for "genetic meltdown", which is an effect predicted by the principle of genetic entropy, instead of evolving into something better. New Work by Richard Lenski: Excerpt: Interestingly, in this paper they report that the E. coli strain became a “mutator.” That means it lost at least some of its ability to repair its DNA, so mutations are accumulating now at a rate about seventy times faster than normal. *******www.evolutionnews****/2009/10/new_work_by_richard_lenski.html Evolution vs. Genetic Entropy - video *******www.youtube****/watch?v=mmbRbyv2PA0 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
25 Jan 2010
1327
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‘Darwinian evolution is impossible’ - John Sanford - Geneticist ‘Mutations are word-processing errors in the cell’s instruction manual. Mutations systematically destroy genetic information—even as word processing errors destroy written information. While there are some rare beneficial mutations (Even the rare beneficial mutations still lose information), bad mutations outnumber them—perhaps by a million to one. So even allowing for beneficial mutations, the net effect of mutation is overwhelmingly deleterious. The more the mutations, the less the information. This is fundamental to the mutation process.’ *******creation****/geneticist-evolution-impossible Random Mutations Destroy Information - Perry Marshall - video *******www.metacafe****/watch/4023143/random_mutations_destroy_information_perry_marshall/ "The neo-Darwinians would like us to believe that large evolutionary changes can result from a series of small events if there are enough of them. But if these events all lose information they can’t be the steps in the kind of evolution the neo-Darwin theory is supposed to explain, no matter how many mutations there are. Whoever thinks macroevolution can be made by mutations that lose information is like the merchant who lost a little money on every sale but thought he could make it up on volume." Lee Spetner (Ph.D. Physics - MIT - Not By Chance) “But there is no evidence that DNA mutations can provide the sorts of variation needed for evolution… There is no evidence for beneficial mutations at the level of macroevolution, but there is also no evidence at the level of what is commonly regarded as microevolution.” Jonathan Wells (PhD. - Molecular Biology) As former president of the French Academy of Sciences Pierre P. Grasse has stated: “What is the use of their unceasing mutations, if they do not change? In sum, the mutations of bacteria and viruses are merely hereditary fluctuations around a median position; a swing to the right, a swing to the left, but no final evolutionary effect.” The Sheer Lack Of Evidence For Macro Evolution - William Lane Craig - video *******www.metacafe****/watch/4023134/the_sheer_lack_of_evidence_for_macro_evolution_william_lane_craig/ In fact, from consistent findings such as these, it is increasingly apparent the principle of Genetic Entropy is the overriding foundational rule for all of biology, with no exceptions at all, and belief in "truly" beneficial mutations is nothing more than wishful speculation on the materialist part which has no foundation in empirical science whatsoever. The Capabilities of Chaos and Complexity: David L. Abel - Null Hypothesis For Information Generation - 2009 To focus the scientific community’s attention on its own tendencies toward overzealous metaphysical imagination bordering on “wish-fulfillment,” we propose the following readily falsifiable null hypothesis, and invite rigorous experimental attempts to falsify it: "Physicodynamics cannot spontaneously traverse The Cybernetic Cut: physicodynamics alone cannot organize itself into formally functional systems requiring algorithmic optimization, computational halting, and circuit integration." A single exception of non trivial, unaided spontaneous optimization of formal function by truly natural process would falsify this null hypothesis. *******www.mdpi****/1422-0067/10/1/247/pdf *******mdpi****/1422-0067/10/1/247/ag Evolution vs. Genetic Entropy - video *******www.metacafe****/watch/4028086/evolution_vs_genetic_entropy/ Here is a site that gives a clear example of what Dr. Sanford means by Poly-Functional equals Poly-Contrained: Poly-Functional Complexity equals Poly-Constrained Complexity *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjdoZmd2emZncQ For a broad outline of the "Fitness test", required to be passed to show a violation of the principle of Genetic Entropy, please see the following video and articles: Is Antibiotic Resistance evidence for evolution? - "The Fitness Test" - video *******www.metacafe****/watch/3995248/is_antibiotic_resistance_evidence_for_evolution_the_fitness_test/ Testing the Biological Fitness of Antibiotic Resistant Bacteria - 2008 *******www.answersingenesis****/articles/aid/v2/n1/darwin-at-drugstore List Of Degraded Molecular Abilities Of Antibiotic Resistant Bacteria: *******www.trueorigin****/bacteria01.asp The foundational rule of Genetic Entropy for biology, which can draw its foundation in science from the twin pillars of the Second Law of Thermodynamics and from the Law of Conservation of Information (Dembski, Marks), can be stated something like this: "All beneficial adaptations away from a parent species for a sub-species, which increase fitness to a particular environment, will always come at a loss of the optimal functional information that was originally created in the parent species genome." Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/ So where did the information come from if not by mutations? John 1:1 "In the beginning was The Word,,,
3 Oct 2011
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The artificial imposition of the materialistic philosophy onto the scientific method has blinded many scientists to the inference of God as a rational explanation in these questions of origins. In fact, the scientific method, by itself, makes absolutely no predictions as to what the best explanation will be prior to investigation in these question of origins. In the beginning of a investigation all answers are equally valid to the scientific method. Yet scientists have grown accustomed through the years to the artificial imposition of the materialistic philosophy onto the scientific method. That is to say by limiting the answers one may conclude to only materialistic ones, the scientific method has been very effective at solving many puzzles very quickly. This imposition of the materialistic philosophy onto the scientific method has indeed led to many breakthroughs of technology which would not have been possible had the phenomena been presumed to be solely the work of a miracle. This imposition of materialism onto the scientific method is usually called methodological naturalism, methodological materialism, or scientific materialism etc... Yet today, due to the impressive success of methodological naturalism in our everyday lives, many scientists are unable to separate this artificial imposition of the materialistic philosophy from the scientific method in this completely different question of origins. A Question for Barbara Forrest *******darwins-god.blogspot****/2009/06/question-for-barbara-forrest.html In fact, I've heard someone say, "Science is materialism." Yet science clearly is not materialism. Materialism is a philosophy which makes the dogmatic assertion that only blind material processes generated everything around us, including ourselves. Materialism is thus in direct opposition to Theism which holds that God purposely created us in His image. Furthermore science, or more particularly the scientific method, in reality, only cares to relentlessly pursue the truth and could care less if the answer is a materialistic one or not. This is especially true in these questions of origins, since we are indeed questioning the materialistic philosophy itself. i.e. We are asking the scientific method to answer this very specific question, "Did God create us or did blind material processes create us?" When we realize this is the actual question we are seeking an answer to within the scientific method, then of course it is readily apparent we cannot impose strict materialistic answers onto the scientific method prior to investigation. In fact when looking at the evidence in this light we find out many interesting things which scientists, who have been blinded by the philosophy of materialism, miss. This is because the materialistic and Theistic philosophy make, and have made, several natural contradictory predictions about what evidence we will find. These predictions, and the evidence we have found, can be tested against one another within the scientific method. For a quick overview here are a few: 1.Materialism predicted an eternal universe, Theism predicted a created universe. - Big Bang points to a creation event. - 2. Materialism predicted time had an infinite past, Theism predicted time had a creation - Time was created in the Big Bang. - 3. Materialism predicted space has always existed, Theism predicted space had a creation (Psalm 89:12) - Space was created in the Big Bang. - 4. Materialism predicted at the base of physical reality would be a solid indestructible material particle which rigidly obeyed the rules of time and space, Theism predicted the basis of this reality was created by a infinitely powerful and transcendent Being who is not limited by time and space - Quantum mechanics reveals a wave/particle duality for the basis of our reality which blatantly defies our concepts of time and space. - 5. Materialism predicted the rate at which time passed was constant everywhere in the universe, Theism predicted God is eternal and is outside of time - Special Relativity has shown that time, as we understand it, is relative and comes to a complete stop at the speed of light. (Psalm 90:4)- 6. Materialism predicted the universe did not have life in mind and life was ultimately an accident of time and chance. Theism predicted this universe was purposely created by God with man in mind - Every transcendent universal constant scientists can measure is exquisitely fine-tuned for carbon-based life to exist in this universe. - 7. Materialism predicted complex life in this universe should be fairly common. Theism predicted the earth is extremely unique in this universe - Statistical analysis of the hundreds of required parameters which enable complex life to be possible on earth gives strong indication the earth is extremely unique in this universe. - 8. Materialism predicted much of the DNA code was junk. Theism predicted we are fearfully and wonderfully made - ENCODE research into the DNA has revealed a "biological jungle deeper, denser, and more difficult to penetrate than anyone imagined.". - 9. Materialism predicted a extremely beneficial and flexible mutation rate for DNA which was ultimately responsible for all the diversity and complexity of life we see on earth. Theism predicted only God created life on earth - The mutation rate to DNA is overwhelmingly detrimental. Detrimental to such a point that it is seriously questioned whether there are any truly beneficial mutations whatsoever. (M. Behe; JC Sanford) - 10. Materialism predicted a very simple first life form which accidentally came from "a warm little pond". Theism predicted God created life - The simplest life ever found on Earth is far more complex than any machine man has made through concerted effort. (Michael Denton PhD) - 11. Materialism predicted it took a very long time for life to develop on earth. Theism predicted life to appear abruptly on earth after water appeared on earth (Genesis 1:10-11) - We find evidence for complex photo-synthetic life in the oldest sedimentary rocks ever found on earth - 12. Materialism predicted the gradual unfolding of life to be self-evident in the fossil record. Theism predicted complex and diverse life to appear abruptly in the seas in God's fifth day of creation. - The Cambrian Explosion shows a sudden appearance of many different and completely unique fossils within a very short "geologic resolution time" in the Cambrian seas. - 13. Materialism predicted there should be numerous transitional fossils found in the fossil record, Theism predicted sudden appearance and rapid diversity within different kinds found in the fossil record - Fossils are consistently characterized by sudden appearance of a group/kind in the fossil record, then rapid diversity within the group/kind, and then long term stability and even deterioration of variety within the overall group/kind, and within the specific species of the kind, over long periods of time. Of the few dozen or so fossils claimed as transitional, not one is uncontested as a true example of transition between major animal forms out of millions of collected fossils. - 14. Materialism predicted animal speciation should happen on a somewhat constant basis on earth. Theism predicted man was the last species created on earth - Man himself is the last generally accepted major fossil form to have suddenly appeared in the fossil record. - As you can see when we remove the artificial imposition of the materialistic philosophy, from the scientific method, and look carefully at the predictions of both the materialistic philosophy and the Theistic philosophy, side by side, we find the scientific method is very good at pointing us in the direction of Theism as the true explanation. - Last, but certainly not least, as a Christian I would be very remiss if I failed to ask you to accept the free gift of eternal life from the living God who created this universe and all life in it. In fact, almighty God has made a very clear path for us "fallen human adults" to completely reconcile with Him so we may be able to stand before Him in heaven. We do this by humbly accepting what He has done for us through Christ on the cross so that we may be able to stand in the glory of the presence of almighty God in heaven (For our God is an all-consuming fire - Hebrews 12:29). In fact by accepting Christ into your heart, you will be cleansed spotless of your sins in the presence of almighty God. So how about it, Will you accept this priceless gift of Jesus Christ into your heart today so you may able to receive the priceless gift of eternal life in heaven? --- Revelation 3:20 'Behold, I stand at the door and knock; if anyone hears My voice and opens the door, I will come in to him and will dine with him, and he with Me.' John 3:16 For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him shall not perish, but have everlasting life. *******docs.google****/Doc?docid=dc8z67wz_5fwz42dg9 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
16 Feb 2011
2598
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Genetic Entropy & the Mystery of the Genome - Book Review *******www.tccsa.tc/articles/genetic_entropy.html John C. Sanford - Bio Excerpt: * Co-developer of “Mendel’s Accountant” – today’s most advanced forward-time population genetics simulation program * Primary inventor of the biolistic (gene gun) process * Co-inventor of the Pathogen-derived Resistance (PDR) process * Co-inventor of the Genetic Vaccination process * Primary inventor of numerous conventionally-bred fruit varieties * Most of the world's transgenic crop acreage were transformed via my biolistic process *******www.nysaes***rnell.edu/hort/faculty/sanford/ This following study confirmed the "detrimental" mutation rate for humans, of 100 to 300, estimated by John Sanford in his book "Genetic Entropy" in 2005: Human mutation rate revealed: August 2009 Every time human DNA is passed from one generation to the next it accumulates 100–200 new mutations, according to a DNA-sequencing analysis of the Y chromosome. (Of note: this number is derived after "compensatory mutations") *******www.nature****/news/2009/090827/full/news.2009.864.html This mutation rate of 100 to 200 is far greater than even what evolutionists agree is an acceptable mutation rate for an organism: Beyond A 'Speed Limit' On Mutations, Species Risk Extinction Excerpt: Shakhnovich's group found that for most organisms, including viruses and bacteria, an organism's rate of genome mutation must stay below 6 mutations per genome per generation to prevent the accumulation of too many potentially lethal changes in genetic material. *******www.sciencedaily****/releases/2007/10/071001172753.htm Professional evolutionary biologists are hard-pressed to cite even one clear-cut example of evolution through a beneficial mutation to the DNA of humans which would violate the principle of genetic entropy. Although a materialist may try to claim the lactase persistence mutation as a lonely example of a "truly" beneficial mutation in humans, lactase persistence is actually a loss of a instruction in the genome to turn the lactase enzyme off, so the mutation clearly does not violate Genetic Entropy. Yet at the same time, the evidence for the detrimental nature of mutations in humans is overwhelming for doctors have already cited over 3500 mutational disorders (Dr. Gary Parker). (of note: this figure is now known to be over 6000 mendelian mutational disorders - John Sanford - 2010) "Mutations" by Dr. Gary Parker Excerpt: human beings are now subject to over 3500 mutational disorders. (Now known to be over 6000 - John Sanford - 2010) *******www.answersingenesis****/home/area/cfol/ch2-mutations.asp Using Computer Simulation to Understand Mutation Accumulation Dynamics and Genetic Load: Excerpt: We apply a biologically realistic forward-time population genetics program to study human mutation accumulation under a wide-range of circumstances. Using realistic estimates for the relevant biological parameters, we investigate the rate of mutation accumulation, the distribution of the fitness effects of the accumulating mutations, and the overall effect on mean genotypic fitness. Our numerical simulations consistently show that deleterious mutations accumulate linearly across a large portion of the relevant parameter space. *******bioinformatics.cau.edu.cn/lecture/chinaproof.pdf MENDEL’S ACCOUNTANT: J. SANFORD†, J. BAUMGARDNER‡, W. BREWER§, P. GIBSON¶, AND W. REMINE *******mendelsaccount.sourceforge**** *******www.scpe****/vols/vol08/no2/SCPE_8_2_02.pdf Human Evolution - Genetic Adam And Eve - Hugh Ross - video *******www.metacafe****/watch/4036776 Human Evolution? - The Compelling Genetic, Fossil Evidence & Tool Making For Adam and Eve - Dr. Fazale Rana - video *******www.metacafe****/watch/4284482 Does human genetic evidence support Noah's flood? Fazale Rana - video *******www.metacafe****/watch/4116168 Tracing Your Ancestors Through History - Noah's Descendants - video *******edinburghcreationgroup****/ancestors.xml TABLE OF NATIONS (GENEALOGY OF MANKIND) by Tim Osterholm Excerpt: The fact is, that wherever its statements can be sufficiently tested, Genesis 10 of the Bible has been found completely accurate; resulting partly from linguistic studies, partly from archaeology, and, more recently still, from the findings of physical anthropologists, who are, to this day, recovering important clues to lines of migration in ancient historic times. As implied in verse 32 of Genesis 10, this Table includes everybody; meaning that so-called fossil man, primitive peoples (ancient and modern) and modern man are all derived from Noah's three sons, Shem, Ham, and Japheth. *******www.soundchristian****/man/ Startling Evidence That Noah's Flood Really Happened - video *******video.google****/videoplay?docid=-7075979791519871387 Even evolutionists admit the fossil record does not reveal a gradual process of monkeys evolving into humans: Evolution of the Genus Homo - Annual Review of Earth and Planetary Sciences - Tattersall, Schwartz, May 2009 Excerpt: "Definition of the genus Homo is almost as fraught as the definition of Homo sapiens. We look at the evidence for “early Homo,” finding little morphological basis for extending our genus to any of the 2.5–1.6-myr-old fossil forms assigned to “early Homo” or Homo habilis/rudolfensis." *******arjournals.annualreviews****/doi/abs/10.1146/annurev.earth.031208.100202 "When we consider the remote past, before the origin of the actual species Homo sapiens, we are faced with a fragmentary and disconnected fossil record. Despite the excited and optimistic claims that have been made by some paleontologists, no fossil hominid species can be established as our direct ancestor." Richard Lewontin - Harvard Zoologist *******www.discovery****/a/9961 The following video is downright eye-opening with its evidence for Biblical authenticity: The Physical Ashen Remains Of Sodom and Gomorrah - video *******www.youtube****/watch?v=FwTVFk1HK3Y The entire 49 min. video by John Sanford may be ordered here: The Mystery of Our Declining Genes DVD ********store.creation****/us/product_info.php?sku=30-9-583 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
6 May 2010
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6:26
Genetic Entropy & the Mystery of the Genome - Book Review *******www.tccsa.tc/articles/genetic_entropy.html John C. Sanford - Bio Excerpt: * Co-developer of “Mendel’s Accountant” – today’s most advanced forward-time population genetics simulation program * Primary inventor of the biolistic (gene gun) process * Co-inventor of the Pathogen-derived Resistance (PDR) process * Co-inventor of the Genetic Vaccination process * Primary inventor of numerous conventionally-bred fruit varieties * Most of the world's transgenic crop acreage were transformed via my biolistic process *******www.nysaes***rnell.edu/hort/faculty/sanford/ The entire 49 min. video by John Sanford may be ordered here: The Mystery of Our Declining Genes DVD ********store.creation****/us/product_info.php?sku=30-9-583 Natural Selection Reduces Genetic Information - Dr. Georgia Purdom - video *******www.metacafe****/watch/4036808 Natural Selection Reduces Genetic Information - No Beneficial Mutations - Spetner - Denton - video *******www.metacafe****/watch/4036816 Survival of the fittest theory: Darwinism’s limits – Jerry Fodor and Massimo Piattelli-Palmarini – Feb 2010 Excerpt: Much of the vast neo-Darwinian literature is distressingly uncritical. The possibility that anything is seriously amiss with Darwin’s account of evolution is hardly (ever) considered. ,,, Natural Selection has shown insidious imperialistic tendencies. *******www.newscientist****/article/mg20527466.100-survival-of-the-fittest-theory-darwinisms-limits.html This following study is very interesting for the researcher surveyed 130 DNA-based evolutionary trees to see if "natural selection" results in speciation and found: Accidental origins: Where species come from - March 2010 Excerpt: If speciation results from natural selection via many small changes, you would expect the branch lengths to fit a bell-shaped curve.,,, Instead, Pagel's team found that in 78 per cent of the trees, the best fit for the branch length distribution was another familiar curve, known as the exponential distribution. Like the bell curve, the exponential has a straightforward explanation - but it is a disquieting one for evolutionary biologists. The exponential is the pattern you get when you are waiting for some single, infrequent event to happen.,,,To Pagel, the implications for speciation are clear: "It isn't the accumulation of events that causes a speciation, it's single, rare events falling out of the sky, so to speak." *******www.newscientist****/article/mg20527511.400-accidental-origins-where-species-come-from.html?page=2 The Strength of Phenotypic Selection in Natural Populations This review demonstrates that our information about the strength of phenotypic selection in natural populations has increased dramatically in the past 2 decades, but many important issues about selection remain unresolved. *******www.oeb.harvard.edu/faculty/hoekstra/PDFs/Kingsolver2001AmNat.pdf EXPELLED - Natural Selection And Genetic Mutations - video *******www.metacafe****/watch/4036840 "...but Natural Selection reduces genetic information and we know this from all the Genetic Population studies that we have..." Maciej Marian Giertych - Population Geneticist - member of the European Parliament - EXPELLED Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
7 May 2010
1676
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5:37
DNA - Poly-Functional Complexity equals Poly-Constrained Complexity *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjdoZmd2emZncQ As former president of the French Academy of Sciences Pierre P. Grasse has stated: “What is the use of their unceasing mutations, if they do not change? In sum, the mutations of bacteria and viruses are merely hereditary fluctuations around a median position; a swing to the right, a swing to the left, but no final evolutionary effect.” Random Mutations Destroy Information - Perry Marshall - video *******www.metacafe****/watch/4023143 Needless to say, this limit to the variability of "simple" single cell organism, bacteria, and viruses, is extremely bad news for the materialist. Materialists simply do not have the "beneficial" mutations they need to make evolution work. The following site has numerous quotes, studies and videos which reveal the overwhelmingly negative mutation rate which has been found in life: Mutation Studies, Videos, And Quotes *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjZjZnM5M21mZg Evolution vs. Genetic Entropy - video *******www.metacafe****/watch/4028086 Assessing the NCSE’s Citation Bluffs on the Evolution of New Genetic Information - Feb. 2010 *******www.evolutionnews****/2010/02/assessing_the_ncses_citation_b.html How to Play the Gene Evolution Game - Casey Luskin - Feb. 2010 *******www.evolutionnews****/2010/02/how_to_play_the_gene_evolution.html The NCSE, Judge Jones, and Bluffs About the Origin of New Functional Genetic Information - Casey Luskin - March 2010 *******www.discovery****/a/14251 It should be noted that evolutionists like to play head games with Claude Shannon's broad definition of information since "non-functional" information bits may be considered information in his broad definition, yet when looked at carefully, Shannon's work actually fully supports Intelligent Design as is illustrated in the following video and article: DNA and The Genetic Code Pt 3 - Perry Marshall - video *******www.youtube****/watch?v=FtMQUFOwEFo Skeptic's Objection to Information Theory #1: "DNA is Not a Code" *******cosmicfingerprints****/dnanotcode.htm DNA – The Genetic Code – Optimal Error Minimization & Parallel Codes – Dr. Fazale Rana – video *******www.metacafe****/watch/4491422 Here, we show that the universal genetic code can efficiently carry arbitrary parallel codes much better than the vast majority of other possible genetic codes…. the present findings support the view that protein-coding regions can carry abundant parallel codes. *******genome.cshlp****/content/17/4/405.full The data compression of some stretches of human DNA is estimated to be up to 12 codes thick (12 different ways of DNA transcription) (Trifonov, 1989). (This is well beyond the complexity of any computer code ever written by man). John Sanford – Genetic Entropy The multiple codes of nucleotide sequences. Trifonov EN. – 1989 Excerpt: Nucleotide sequences carry genetic information of many different kinds, not just instructions for protein synthesis (triplet code). *******www.ncbi.nlm.nih.gov/pubmed/2673451 Dr. Jerry Bergman, “Divine Engineering: Unraveling DNA’s Design”: The DNA packing process is both complex and elegant and is so efficient that it achieves a reduction in length of DNA by a factor of 1 million. DNA Wrapping (Histone Protein Wrapping to Cell Division)- video *******www.youtube****/watch?v=gbSIBhFwQ4s Human DNA is like a computer program but far, far more advanced than any software we’ve ever created. Bill Gates, The Road Ahead, 1996, p. 188 The Coding Found In DNA Surpasses Man’s Ability To Code – Stephen Meyer – video *******www.metacafe****/watch/4050638 Bill Gates, in recognizing the superiority found in Genetic Coding, compared to the best computer coding we now have, has now funded research into this area: Welcome to CoSBi – (Computational and Systems Biology) Excerpt: Biological systems are the most parallel systems ever studied and we hope to use our better understanding of how living systems handle information to design new computational paradigms, programming languages and software development environments. The net result would be the design and implementation of better applications firmly grounded on new computational, massively parallel paradigms in many different areas. Human Genome “Infinitely More Complex” Than Expected – April 2010 Excerpt: Hayden acknowledged that the “junk DNA” paradigm has been blown to smithereens. “Just one decade of post-genome biology has exploded that view,” she said, speaking of the gene regulation was a straightforward, linear process of gene coding for regulator protein that controls transcription. “Biology’s new glimpse at a universe of non-coding DNA – what used to be called ‘junk’ DNA – has been fascinating and befuddling.” If it’s junk, why would the human body decode 74% to 93& of it? Inside the Human Genome: A Case for Non-Intelligent Design – Pg. 57 By John C. Avise Excerpt: “Another compilation of gene lesions responsible for inherited diseases is the web-based Human Gene Mutation Database (HGMD). Recent versions of HGMD describe more than 75,000 different disease causing mutations identified to date in Homo-sapiens.” HGMD®: Now celebrating our 100,000 mutation milestone! *******www.hgmd.cf.ac***/ac/index.php I really question their use of the word “celebrating”. The burning question is where in the world are all the hypothetical beneficial mutations??? The two most popular examples given Sickle cell and Lactase persistence, Sickle Cell is only beneficial in a limited sense and clearly detrimental in a molecular sense. Whereas Lactase persistence is the same in that it confers an advantage but it loses information in the genome for turning the lactase enzyme off. thus both of the most popular examples cited by evolutionists lose functional information. Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/
14 May 2010
1267
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8:00
Entire video: *******www.mefeedia****/watch/32748037 Bacterial Flagellum - A Sheer Wonder Of Intelligent Design - video *******www.metacafe****/watch/3994630 Michael Behe on Falsifying Intelligent Design - video *******www.youtube****/watch?v=N8jXXJN4o_A Astonishingly, actual motors, which far surpass man-made motors in 'engineering parameters', are now being found inside 'simple cells'. Articles and Videos on Molecular Motors *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMzlkNjYydmRkZw&hl=en "There are no detailed Darwinian accounts for the evolution of any fundamental biochemical or cellular system only a variety of wishful speculations. It is remarkable that Darwinism is accepted as a satisfactory explanation of such a vast subject." James Shapiro - Molecular Biologist “The response I have received from repeating Behe's claim about the evolutionary literature, which simply brings out the point being made implicitly by many others, such as Chris Dutton and so on, is that I obviously have not read the right books. There are, I am sure, evolutionists who have described how the transitions in question could have occurred.” And he continues, “When I ask in which books I can find these discussions, however, I either get no answer or else some titles that, upon examination, do not, in fact, contain the promised accounts. That such accounts exist seems to be something that is widely known, but I have yet to encounter anyone who knows where they exist.” David Ray Griffin - retired professor of philosophy of religion and theology Michael Behe - Life Reeks Of Design - 2010 - video *******www.metacafe****/watch/5066181 William Dembski PhD., and Robert Marks PhD., website with peer reviewed 'Conservation Of Information' Papers (caution heavy math): *******www.evoinfo****/ Dr. Behe states in The Edge of Evolution on page 135: "Generating a single new cellular protein-protein binding site (in other words, generating a truly beneficial mutational event that would actually explain the generation of the complex molecular machinery we see in life) is of the same order of difficulty or worse than the development of chloroquine resistance in the malarial parasite." That order of difficulty is put at 10^20 replications of the malarial parasite by Dr. Behe. This number comes from direct empirical observation. Richard Dawkins’ The Greatest Show on Earth Shies Away from Intelligent Design but Unwittingly Vindicates Michael Behe - Oct. 2009 Excerpt: The rarity of chloroquine resistance is not in question. In fact, Behe’s statistic that it occurs only once in every 10^20 cases was derived from public health statistical data, published by an authority in the Journal of Clinical Investigation. The extreme rareness of chloroquine resistance is not a negotiable data point; it is an observed fact. *******www.evolutionnews****/2009/10/richard_dawkins_the_greatest_s.html Waiting Longer for Two Mutations - Michael J. Behe Excerpt: Citing malaria literature sources (White 2004) I had noted that the de novo appearance of chloroquine resistance in Plasmodium falciparum was an event of probability of 1 in 10^20. I then wrote that ‘‘for humans to achieve a mutation like this by chance, we would have to wait 100 million times 10 million years’’ (Behe 2007) (because that is the extrapolated time that it would take to produce 10^20 humans). Durrett and Schmidt (2008, p. 1507) retort that my number ‘‘is 5 million times larger than the calculation we have just given’’ using their model (which nonetheless "using their model" gives a prohibitively long waiting time of 216 million years). Their criticism compares apples to oranges. My figure of 10^20 is an empirical statistic from the literature; it is not, as their calculation is, a theoretical estimate from a population genetics model. *******www.discovery****/a/9461 This following calculation by geneticist John Sanford for 'fixing' a beneficial mutation, or for creating a new gene, in humans, gives equally absurd numbers that once again render the Darwinian scenario of humans evolving from apes completely false: Dr. Sanford calculates it would take 12 million years to “fix” a single base pair mutation into a population. He further calculates that to create a gene with 1000 base pairs, it would take 12 million x 1000 or 12 billion years. This is obviously too slow to support the creation of the human genome containing 3 billion base pairs. *******www.detectingtruth****/?p=66 Whale Evolution Vs. Population Genetics - Richard Sternberg PhD. in Evolutionary Biology - video *******www.metacafe****/watch/4165203 An Atheist Interviews Michael Behe About "The Edge Of Evolution" - video *******www.in****/videos/watchvideo-bloggingheads-interview-with-michael-behe-4734623.html Michael Behe's Amazon Blog *******www.amazon****/gp/blog/A3DGRQ0IO7KYQ2/ref=cm_blog_blog/180-3515567-6480413 Michael Behe - bio. and list of peer reviewed papers: *******www.lehigh.edu/~inbios/faculty/behe.html Should Intelligent Design Be Taught as Science? Michael Behe debates Stephen Barr - 2010 - video *******www.isi****/lectures/flvplayer/lectureplayer.aspx?file=v000355_cicero_040710.mp4&dir=mp4/lectures Main page - with audio of debate *******www.isi****/lectures/lectures.aspx?SBy=lecture&SFor=18fdfd28-e682-421f-9acf-2940402af8e3 Peer-Reviewed & Peer-Edited Scientific Publications Supporting the Theory of Intelligent Design (Annotated) - updated regularly *******www.discovery****/a/2640 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/2009/10/intelligent-design-anthropic-hypothesis_19.html Stephen Meyer - Functional Proteins And Information For Body Plans - video *******www.metacafe****/watch/4050681 This following video is a bit more clear for explaining exactly why mutations to the DNA do not control Body Plan morphogenesis, since the mutations are the ‘bottom rung of the ladder’ as far as the 'higher levels of the layered information’ of the cell are concerned: Stephen Meyer on Craig Venter, Complexity Of The Cell & Layered Information *******www.metacafe****/watch/4798685
7 Oct 2010
1694
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9:55
Stephen C. Meyer - The Scientific Basis For Intelligent Design - video *******www.metacafe****/watch/4104651/ Stephen C. Meyer - Signature In The Cell: "DNA functions like a software program," "We know from experience that software comes from programmers. Information--whether inscribed in hieroglyphics, written in a book or encoded in a radio signal--always arises from an intelligent source. So the discovery of digital code in DNA provides evidence that the information in DNA also had an intelligent source." *******www.evolutionnews****/2009/07/leading_advocate_of_intelligen.html Michael Behe on Falsifying Intelligent Design - video *******www.youtube****/watch?v=N8jXXJN4o_A ,,,we must concede that there are presently no detailed Darwinian accounts of the evolution of any biochemical or cellular system, only a variety of wishful speculations.’ Franklin M. Harold,* 2001. The way of the cell: molecules, organisms and the order of life, Oxford University Press, New York, p. 205. *Professor Emeritus of Biochemistry, Colorado State University, USA Michael Behe - No Scientific Literature For Evolution of Any Irreducibly Complex Molecular Machines *******www.metacafe****/watch/5302950/ Astonishingly, actual motors, which far surpass man-made motors in 'engineering parameters', are now being found inside 'simple cells'. Bacterial Flagellum - A Sheer Wonder Of Intelligent Design - video *******www.metacafe****/watch/3994630 Bacterial Flagella: A Paradigm for Design – Scott Minnich – Video *******www.vimeo****/9032112 Articles and Videos on Molecular Motors *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMzlkNjYydmRkZw&hl=en There are no detailed Darwinian accounts for the evolution of any fundamental biochemical or cellular system only a variety of wishful speculations. It is remarkable that Darwinism is accepted as a satisfactory explanation of such a vast subject." James Shapiro - Molecular Biologist “The response I have received from repeating Behe's claim about the evolutionary literature, which simply brings out the point being made implicitly by many others, such as Chris Dutton and so on, is that I obviously have not read the right books. There are, I am sure, evolutionists who have described how the transitions in question could have occurred.” And he continues, “When I ask in which books I can find these discussions, however, I either get no answer or else some titles that, upon examination, do not, in fact, contain the promised accounts. That such accounts exist seems to be something that is widely known, but I have yet to encounter anyone who knows where they exist.” David Ray Griffin - retired professor of philosophy of religion and theology Michael Behe - Life Reeks Of Design - 2010 - video *******www.metacafe****/watch/5066181 William Dembski PhD., and Robert Marks PhD., website with peer reviewed 'Conservation Of Information' Papers (caution heavy math): *******www.evoinfo****/ Dr. Behe states in The Edge of Evolution on page 135: "Generating a single new cellular protein-protein binding site (in other words, generating a truly beneficial mutational event that would actually explain the generation of the complex molecular machinery we see in life) is of the same order of difficulty or worse than the development of chloroquine resistance in the malarial parasite." That order of difficulty is put at 10^20 replications of the malarial parasite by Dr. Behe. This number comes from direct empirical observation. Richard Dawkins’ The Greatest Show on Earth Shies Away from Intelligent Design but Unwittingly Vindicates Michael Behe - Oct. 2009 Excerpt: The rarity of chloroquine resistance is not in question. In fact, Behe’s statistic that it occurs only once in every 10^20 cases was derived from public health statistical data, published by an authority in the Journal of Clinical Investigation. The extreme rareness of chloroquine resistance is not a negotiable data point; it is an observed fact. *******www.evolutionnews****/2009/10/richard_dawkins_the_greatest_s.html Waiting Longer for Two Mutations - Michael J. Behe Excerpt: Citing malaria literature sources (White 2004) I had noted that the de novo appearance of chloroquine resistance in Plasmodium falciparum was an event of probability of 1 in 10^20. I then wrote that ‘‘for humans to achieve a mutation like this by chance, we would have to wait 100 million times 10 million years’’ (Behe 2007) (because that is the extrapolated time that it would take to produce 10^20 humans). Durrett and Schmidt (2008, p. 1507) retort that my number ‘‘is 5 million times larger than the calculation we have just given’’ using their model (which nonetheless "using their model" gives a prohibitively long waiting time of 216 million years). Their criticism compares apples to oranges. My figure of 10^20 is an empirical statistic from the literature; it is not, as their calculation is, a theoretical estimate from a population genetics model. *******www.discovery****/a/9461 This following calculation by geneticist John Sanford for 'fixing' a beneficial mutation, or for creating a new gene, in humans, gives equally absurd numbers that once again render the Darwinian scenario of humans evolving from apes completely false: Dr. Sanford calculates it would take 12 million years to “fix” a single base pair mutation into a population. He further calculates that to create a gene with 1000 base pairs, it would take 12 million x 1000 or 12 billion years. This is obviously too slow to support the creation of the human genome containing 3 billion base pairs. *******www.detectingtruth****/?p=66 Whale Evolution Vs. Population Genetics - Richard Sternberg PhD. in Evolutionary Biology - video *******www.metacafe****/watch/4165203 Materialists simply do not have the 'beneficial' mutations they need to make evolution work. The following site has numerous quotes, studies and videos which reveal the overwhelmingly negative mutation rate which has been found in life: Mutation Studies, Videos, And Quotes *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjZjZnM5M21mZg An Atheist Interviews Michael Behe About "The Edge Of Evolution" - video *******www.in****/videos/watchvideo-bloggingheads-interview-with-michael-behe-4734623.html Michael Behe's Amazon Blog *******www.amazon****/gp/blog/A3DGRQ0IO7KYQ2/ref=cm_blog_blog/180-3515567-6480413 Michael Behe - bio. and list of peer reviewed papers: *******www.lehigh.edu/~inbios/faculty/behe.html Should Intelligent Design Be Taught as Science? Michael Behe debates Stephen Barr - 2010 - video *******www.isi****/lectures/flvplayer/lectureplayer.aspx?file=v000355_cicero_040710.mp4&dir=mp4/lectures Main page - with audio of debate *******www.isi****/lectures/lectures.aspx?SBy=lecture&SFor=18fdfd28-e682-421f-9acf-2940402af8e3 Peer-Reviewed & Peer-Edited Scientific Publications Supporting the Theory of Intelligent Design (Annotated) - updated regularly *******www.discovery****/a/2640 The DNA Code - Solid Scientific Proof Of Intelligent Design - Perry Marshall - video *******www.metacafe****/watch/4060532/the_dna_code_solid_scientific_proof_of_intelligent_design_perry_marshall/ The current materialistic argument essentially appears to be like this: Premise One: No materialistic cause of specified complex information is known. Conclusion: Therefore, it must arise from some unknown materialistic cause. On the other hand, Stephen Meyer describes the intelligent design argument as follows: “Premise One: Despite a thorough search, no material causes have been discovered that demonstrate the power to produce large amounts of specified information. “Premise Two: Intelligent causes have demonstrated the power to produce large amounts of specified information. “Conclusion: Intelligent design constitutes the best, most causally adequate, explanation for the information in the cell.” Stephen Meyer - Extreme Rarity of Functional Proteins And Higher Level Information For Body Plans - video *******www.metacafe****/watch/4050681 This following video is a bit more clear for explaining exactly why mutations to the DNA do not control Body Plan morphogenesis, since the mutations are the ‘bottom rung of the ladder’ as far as the 'higher levels of the layered information’ of the cell are concerned: Stephen Meyer on Craig Venter, Complexity Of The Cell & Layered Information *******www.metacafe****/watch/4798685 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/2009/10/intelligent-design-anthropic-hypothesis_19.html
11 Oct 2010
713
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8:31
"Charles Darwin said (paraphrase), 'If anyone could find anything that could not be had through a number of slight, successive, modifications, my theory would absolutely break down.' Well that condition has been met time and time again. Basically every gene, every protein fold. There is nothing of significance that we can show that can be had in a gradualist way. It's a mirage. None of it happens that way. - Doug Axe PhD. Experimental Evolution in Fruit Flies - October 2010 Excerpt: "This research really upends the dominant paradigm about how species evolve".,,, as stated in regards to the 35 year experimental failure to fixate a single beneficial mutation within fruit flies. *******www.arn****/blogs/index.php/literature/2010/10/07/experimental_evolution_in_fruit_flies Waiting Longer for Two Mutations - Michael J. Behe Excerpt: Citing malaria literature sources (White 2004) I had noted that the de novo appearance of chloroquine resistance in Plasmodium falciparum was an event of probability of 1 in 10^20. I then wrote that ‘‘for humans to achieve a mutation like this by chance, we would have to wait 100 million times 10 million years’’ (Behe 2007) (because that is the extrapolated time that it would take to produce 10^20 humans). Durrett and Schmidt (2008, p. 1507) retort that my number ‘‘is 5 million times larger than the calculation we have just given’’ using their model (which nonetheless "using their model" gives a prohibitively long waiting time of 216 million years). Their criticism compares apples to oranges. My figure of 10^20 is an empirical statistic from the literature; it is not, as their calculation is, a theoretical estimate from a population genetics model. *******www.discovery****/a/9461 Estimating the prevalence of protein sequences adopting functional enzyme folds: Doug Axe: Excerpt: Starting with a weakly functional sequence carrying this signature, clusters of ten side-chains within the fold are replaced randomly, within the boundaries of the signature, and tested for function. The prevalence of low-level function in four such experiments indicates that roughly one in 10^64 signature-consistent sequences forms a working domain. Combined with the estimated prevalence of plausible hydropathic patterns (for any fold) and of relevant folds for particular functions, this implies the overall prevalence of sequences performing a specific function by any domain-sized fold may be as low as 1 in 10^77, adding to the body of evidence that functional folds require highly extraordinary sequences. *******www.ncbi.nlm.nih.gov/pubmed/15321723 Evolution vs. Functional Proteins - Doug Axe - Video *******www.metacafe****/watch/4018222 Stephen Meyer - Functional Proteins And Information For Body Plans - video *******www.metacafe****/watch/4050681 This following video is a bit more clear for explaining exactly why mutations to the DNA do not control Body Plan morphogenesis, since the mutations are the ‘bottom rung of the ladder’ as far as the 'higher levels of the layered information’ of the cell are concerned: Stephen Meyer on Craig Venter, Complexity Of The Cell & Layered Information *******www.metacafe****/watch/4798685 "The evidence for the adaptive divergence of gene switches is still thin. The best case involves the loss of protective armor and spines in sticklebacks, both due to changes in regulatory elements. But these elements represent the loss of traits, rather than the origin of evolutionary novelties...We now know that Hox genes and other transcription factors have many roles besides inducing body pattern, and their overall function in development - let alone in evolution - remains murky." *******www.evolutionnews****/2010/06/scott_f_gilbert_developmental035931.html Here is a more thorough critique of evo-devo: Nature's "Gems": Microevolution Meets Microevolution - Casey Luskin - August 2010 *******www.evolutionnews****/2010/08/nature_gems_microevolution_mee037171.html#more Cortical Inheritance: The Crushing Critique Against Genetic Reductionism - Arthur Jones - video *******www.metacafe****/watch/4187488 Astonishingly, actual motors, which far surpass man-made motors in 'engineering parameters', are now being found inside 'simple cells'. Articles and Videos on Molecular Motors *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMzlkNjYydmRkZw&hl=en Michael Behe - Life Reeks Of Design - 2010 - video *******www.metacafe****/watch/5066181 And in spite of the fact of finding molecular motors permeating the simplest of bacterial life, there are no detailed Darwinian accounts for the evolution of even one such motor or system. "There are no detailed Darwinian accounts for the evolution of any fundamental biochemical or cellular system only a variety of wishful speculations. It is remarkable that Darwinism is accepted as a satisfactory explanation of such a vast subject." James Shapiro - Molecular Biologist The following expert doesn't even hide his very unscientific preconceived philosophical bias against intelligent design,,, ‘We should reject, as a matter of principle, the substitution of intelligent design for the dialogue of chance and necessity,,, Yet at the same time the same expert readily admits that neo-Darwinism has ZERO evidence for the chance and necessity of material processes producing any cellular system whatsoever,,, ,,,we must concede that there are presently no detailed Darwinian accounts of the evolution of any biochemical or cellular system, only a variety of wishful speculations.’ Franklin M. Harold,* 2001. The way of the cell: molecules, organisms and the order of life, Oxford University Press, New York, p. 205. Professor Emeritus of Biochemistry, Colorado State University, USA Michael Behe - No Scientific Literature For Evolution of Any Irreducibly Complex Molecular Machines *******www.metacafe****/watch/5302950/ “The response I have received from repeating Behe's claim about the evolutionary literature, which simply brings out the point being made implicitly by many others, such as Chris Dutton and so on, is that I obviously have not read the right books. There are, I am sure, evolutionists who have described how the transitions in question could have occurred.” And he continues, “When I ask in which books I can find these discussions, however, I either get no answer or else some titles that, upon examination, do not, in fact, contain the promised accounts. That such accounts exist seems to be something that is widely known, but I have yet to encounter anyone who knows where they exist.” David Ray Griffin - retired professor of philosophy of religion and theology Poly-Functional Complexity equals Poly-Constrained Complexity *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjdoZmd2emZncQ DNA - Evolution Vs. Polyfuctionality - video *******www.metacafe****/watch/4614519 Bio-Complexity *******bio-complexity****/ojs/index.php/main/issue/view/24 Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/2009/10/intelligent-design-anthropic-hypothesis_19.html
15 Oct 2010
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Indeed, math is not kind to Darwinism in the least when considering the probability of humans ‘randomly’ evolving: In Barrow and Tippler’s book The Anthropic Cosmological Principle, they list ten steps necessary in the course of human evolut...ion, each of which, is so improbable that if left to happen by chance alone, the sun would have ceased to be a main sequence star and would have incinerated the earth. They estimate that the odds of the evolution (by chance) of the human genome is somewhere between 4 to the negative 180th power, to the 110,000th power, and 4 to the negative 360th power, to the 110,000th power. Therefore, if evolution did occur, it literally would have been a miracle and evidence for the existence of God. William Lane Craig Darwin and the Mathematicians – David Berlinski “The formation within geological time of a human body by the laws of physics (or any other laws of similar nature), starting from a random distribution of elementary particles and the field, is as unlikely as the separation by chance of the atmosphere into its components.” Kurt Gödel, was a preeminent mathematician who is considered one of the greatest to have ever lived. Of Note: Godel was a Theist! *******www.evolutionnews****/2009/11/darwin_and_the_mathematicians027911.html “Darwin’s theory is easily the dumbest idea ever taken seriously by science.” Granville Sewell – Professor Of Mathematics – University Of Texas – El Paso Waiting Longer for Two Mutations – Michael J. Behe Excerpt: Citing malaria literature sources (White 2004) I had noted that the de novo appearance of chloroquine resistance in Plasmodium falciparum was an event of probability of 1 in 10^20. I then wrote that ‘‘for humans to achieve a mutation like this by chance, we would have to wait 100 million times 10 million years’’ (Behe 2007) (because that is the extrapolated time that it would take to produce 10^20 humans). Durrett and Schmidt (2008, p. 1507) retort that my number ‘‘is 5 million times larger than the calculation we have just given’’ using their model (which nonetheless “using their model” gives a prohibitively long waiting time of 216 million years). Their criticism compares apples to oranges. My figure of 10^20 is an empirical statistic from the literature; it is not, as their calculation is, a theoretical estimate from a population genetics model. *******www.discovery****/a/9461 This following calculation by geneticist John Sanford for ‘fixing’ a beneficial mutation, or for creating a new gene, in humans, gives equally absurd numbers that once again render the Darwinian scenario of humans evolving from apes completely false: Dr. Sanford calculates it would take 12 million years to “fix” a single base pair mutation into a population. He further calculates that to create a gene with 1000 base pairs, it would take 12 million x 1000 or 12 billion years. This is obviously too slow to support the creation of the human genome containing 3 billion base pairs. *******www.detectingtruth****/?p=66 The Human Body - You Are Amazing - video *******www.metacafe****/watch/5246456 Fearfully and Wonderfully Made - Glimpses At Human Development In The Womb - video *******www.metacafe****/watch/4249713 Fearfully and Wonderfully Made - (Amazing Trivia) video *******www.metacafe****/watch/5289335/ further notes: Human Evolution? - The Compelling Genetic, Fossil Evidence & Tool Making For Adam and Eve Dr. Fazale Rana - video *******www.metacafe****/watch/4284482 Another strong piece of genetic evidence, for the recent origin of man, is that scientists find the differences of the 'younger' human races (Chinese, Europeans, American Indians, etc.. etc..) are losing genetic information when compared to the original race of humans which is thought to have migrated out of east Africa some 50,000 years ago. "We found an enormous amount of diversity within and between the African populations, and we found much less diversity in non-African populations," Tishkoff told attendees today (Jan. 22) at the annual meeting of the American Association for the Advancement of Science in Anaheim. "Only a small subset of the diversity in Africa is found in Europe and the Middle East, and an even narrower set is found in American Indians." Tishkoff; Andrew Clark, Penn State; Kenneth Kidd, Yale University; Giovanni Destro-Bisol, University "La Sapienza," Rome, and Himla Soodyall and Trefor Jenkins, WITS University, South Africa, looked at three locations on DNA samples from 13 to 18 populations in Africa and 30 to 45 populations in the remainder of the world.- I wonder what Hitler would have thought of that study? Does human genetic evidence support Noah's flood? - Fazale Rana - video *******www.metacafe****/watch/4116168 Book Review; Who Was Adam?: A Creation Model Approach to the Origin of Man: Excerpt: The Bible claims that there was a genetic bottleneck at the Genesis flood. Whereas all females can trace their ancestry back to Eve (through the three wives of Noah's sons), all males trace their Y-chromosomes through Noah (through his three sons). This predicted discrepancy for molecular dates of mitochondrial DNA and Y-chromosome data is actually seen in the scientific literature. *******www.godandscience****/newsletters/2005-09.html Kangaroo genes close to humans Excerpt: Australia's kangaroos are genetically similar to humans,,, "There are a few differences, we have a few more of this, a few less of that, but they are the same genes and a lot of them are in the same order," ,,,"We thought they'd be completely scrambled, but they're not. There is great chunks of the human genome which is sitting right there in the kangaroo genome," *******www.reuters****/article/science%20News/idUSTRE4AH1P020081118 I'm just left wondering exactly where evolutionists should place the kangaroos on their cartoon drawings that show man evolving from apes. The Ape To Man Drawings - Another Blatant Deception of Evolution - video *******www.metacafe****/watch/4236845 Eighty percent of proteins are different between humans and chimpanzees; Gene; Volume 346, 14 February 2005: *******www.ncbi.nlm.nih.gov/pubmed/15716009 Chimps are not like humans - May 2004 Excerpt: the International Chimpanzee Chromosome 22 Consortium reports that 83% of chimpanzee chromosome 22 proteins are different from their human counterparts,,, The results reported this week showed that "83% of the genes have changed between the human and the chimpanzee—only 17% are identical—so that means that the impression that comes from the 1.2% [sequence] difference is [misleading]. In the case of protein structures, it has a big effect," Sakaki said. *******cmbi.bjmu.edu.cn/news/0405/119.htm To put it mildly this huge +80% difference between chimps and humans is more than a slight problem for evolutionary materialists: CHROMOSOME STUDY STUNS EVOLUTIONISTS Excerpt: To their great surprise, Dorit and his associates found no nucleotide differences at all in the non-recombinant part of the Y chromosomes of the 38 men. This non-variation suggests no evolution has occurred in male ancestry. *******www.reasons****/interpreting-genesis/adam-and-eve/chromosome-study-stuns-evolutionists The following link clearly shows why the 'upward' evolution of any kind/species of animal from any other 'lower' kind/species of animal is impossible: Poly-Functional Complexity equals Poly-Constrained Complexity *******docs.google****/Doc?docid=0AYmaSrBPNEmGZGM4ejY3d3pfMjdoZmd2emZncQ DNA - Evolution Vs. Polyfuctionality - video *******www.metacafe****/watch/4614519 Scientists Map All Mammalian Gene Interactions - August 2010 Excerpt: Mammals, including humans, have roughly 20,000 different genes.,,, They found a network of more than 7 million interactions encompassing essentially every one of the genes in the mammalian genome. *******www.sciencedaily****/releases/2010/08/100809142044.htm Chimpanzee? 10-10-2008 - Dr Richard Buggs - research geneticist at the University of Florida ...Therefore the total similarity of the genomes could be below 70%. *******www.idnet****.au/files/pdf/Chimpanzee.pdf Post of interest refuting the 98% genetic similarity claim: *******www.uncommondescent****/intelligent-design/a-simple-statistical-test-for-the-alleged-99-genetic-identity-between-humans-and-chimps/#comment-364779 further notes: "Fossil evidence of human evolutionary history is fragmentary and open to various interpretations. Fossil evidence of chimpanzee evolution is absent altogether". Evolutionist Henry Gee, Editor Nature Magazine - 2001 *******www.nature****/nature/journal/v412/n6843/full/412131a0.html New study suggests big bang theory of human evolution - U of M Press Release Excerpt: "The earliest H. sapiens remains differ significantly from australopithecines in both size and anatomical details. Insofar as we can tell, these changes were sudden and not gradual." University of Michigan anthropologist Milford Wolpoff *******www.ns.umich.edu/Releases/2000/Jan00/r011000b.html The Truth About Human Origins: Excerpt: "It is practically impossible to determine which "family tree" (for human evolution) one should accept. Richard Leakey (of the famed fossil hunting family from Africa) has proposed one. His late mother, Mary Leakey, proposed another. Donald Johanson, former president of the Institute of Human Origins in Berkeley, California, has proposed yet another. And as late as 2001, Meave Leakey (Richard's wife) has proposed still another.,," *******books.google****/books?id=J9pON9yB8HkC&pg=PT28&lpg=PT28 The changing face of genus Homo - Wood; Collard Excerpt: the current criteria for identifying species of Homo are difficult, if not impossible, to operate using paleoanthropological evidence. We discuss alternative, verifiable, criteria, and show that when these new criteria are applied to Homo, two species, Homo habilis and Homo rudolfensis, fail to meet them. *******www3.interscience.wiley****/journal/68503570/abstract When we consider the remote past, before the origin of the actual species Homo sapiens, we are faced with a fragmentary and disconnected fossil record. Despite the excited and optimistic claims that have been made by some paleontologists, no fossil hominid species can be established as our direct ancestor. Richard Lewontin - Harvard Zoologist *******www.discovery****/a/9961 Evolution of the Genus Homo - Annual Review of Earth and Planetary Sciences - Tattersall, Schwartz, May 2009 Excerpt: "Definition of the genus Homo is almost as fraught as the definition of Homo sapiens. We look at the evidence for “early Homo,” finding little morphological basis for extending our genus to any of the 2.5–1.6-myr-old fossil forms assigned to “early Homo” or Homo habilis/rudolfensis." *******arjournals.annualreviews****/doi/abs/10.1146/annurev.earth.031208.100202 Man is indeed as unique, as different from all other animals, as had been traditionally claimed by theologians and philosophers. Evolutionist Ernst Mayr *******www.y-origins****/index.php?p=home_more4 “Something extraordinary, if totally fortuitous, happened with the birth of our species….Homo sapiens is as distinctive an entity as exists on the face of the Earth, and should be dignified as such instead of being adulterated with every reasonably large-brained hominid fossil that happened to come along.” Anthropologist Ian Tattersall (curator at the American Museum of Natural History) This following quotes sum up what materialists appear to be doing with this 'evidence' for human evolution: "But what is the basis for the human evolution thesis put forward by evolutionists? It is the existence of plenty of fossils on which evolutionists are able to build imaginary interpretations. Throughout history, more than 6,000 species of ape have lived, and most of them have become extinct. Today, only 120 species live on the earth. These 6,000 or so species of ape, most of which are extinct, constitute a rich resource for the evolutionists to build imaginary interpretations with." *******www.darwinismrefuted****/origin_of_man.html Human evolution: We know little, and with good reason: "Despite decades of patient work we still know rather little about the evolution of humanity…the remains we have are very scarce and very meager and that means that there are probably lots of different species that existed, lived for hundreds of thousands of years and then became extinct and we know nothing about them…All you need is just one to completely blow apart your well entrenched comfortable idea of the linear progress of evolution." - Henry Gee - Editor Of Nature Magazine - *******post-darwinist.blogspot****/2009/07/human-evolution-we-know-little-and-with.html etc... etc... etc... further notes here: Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/2009/10/intelligent-design-anthropic-hypothesis_19.html
16 Jul 2012
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