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In the following audio podcast, Dr. Stephen Meyer speaks on the insurmountable difficulty of extrapolating the neo-Darwinian mechanism of Random Mutation and Natural Selection as a explanation for the Cambrian Explosion: Dr. Stephen Meyer: Why Are We Still Debating Darwin? pt. 2 - podcast *******intelligentdesign.podomatic****/entry/2012-05-23T13_26_22-07_00 Origin of Biological Information and the Higher Taxonomic Categories By: Stephen C. Meyer; Proceedings of the Biological Society of Washington "To say that the fauna of the Cambrian period appeared in a geologically sudden manner also implies the absence of clear transitional intermediate forms connecting Cambrian animals with simpler pre-Cambrian forms. And, indeed, in almost all cases, the Cambrian animals have no clear morphological antecedents in earlier Vendian or Precambrian fauna (Miklos 1993, Erwin et al. 1997:132, Steiner & Reitner 2001, Conway Morris 2003b:510, Valentine et al. 2003:519-520). Further, several recent discoveries and analyses suggest that these morphological gaps may not be merely an artifact of incomplete sampling of the fossil record (Foote 1997, Foote et al. 1999, Benton & Ayala 2003, Meyer et al. 2003), suggesting that the fossil record is at least approximately reliable (Conway Morris 2003b:505)." *******www.discovery****/a/2177 "We do not know why the “Cambrian explosion” occurred when it did, but we have no reason to think that it had to happen then or had to happen at all." - Stephen Jay Gould - More Reflections in Natural History, p. 139 "The Cambrian Explosion was so short that it is below the resolution of the fossil record. It could have happened overnight. So we don't know the duration of the Cambrian Explosion. We just know that it was very, very, fast." Jonathan Wells - Darwin's Dilemma Quote All skeletalised metazoan phyla appeared in the Cambrian - David Tyler - 2010 Excerpt: This means that Cambrian strata can be said to record examples of all the skeletalized metazoan phyla.,,, Subsequent periods of Earth history may have had more dramatic radiations at the Order, Class or Family level, but there were no further bauplan innovations affecting skeletalized metazoan organisms. *******www.arn****/blogs/index.php/literature/2010/12/09/all_skeletalised_metazoan_phyla_appeared The unscientific hegemony of uniformitarianism - David Tyler - May 2011 Excerpt: The pervasive pattern of natural history: disparity precedes diversity,,,, The summary of results for phyla is as follows. The pattern reinforces earlier research that concluded the Explosion is not an artefact of sampling. Much the same finding applies to the appearance of classes. These data are presented in Figures 1 and 2 in the paper. *******www.arn****/blogs/index.php/literature/2011/05/16/the_unscientific_hegemony_of_uniformitar Investigating Evolution: The Cambrian Explosion Part 1 - video ***********/watch?v=4DkbmuRhXRY Part 2 - video ***********/watch?v=iZFM48XIXnk The Cambrian Explosion - Back To A Miracle! - video *******www.metacafe****/watch/4112218 Darwin's Dilemma - Excellent Cambrian Explosion Movie ***********/watch?v=KWEsW7bO8P4 Darwin's Dilemma Faq Page: Questions about the Cambrian Explosion, Evolution, and Intelligent Design *******www.darwinsdilemma****/pdf/faq.pdf More Problems with TalkOrigins' Response on the Cambrian Explosion - Casey Luskin - May 22, 2012 *******www.evolutionnews****/2012/05/more_problems_w059921.html Exotic Cambrian Animals and Plants and Ediacaran biota- Animated videos *******www.lightproductionsvideo****/Cambrian-Animals.html Fossil Gallery - images of species from Cambrian period - Main Gallery The Main Gallery is a comprehensive source of information based on the latest scientific research covering the majority of species so far described from the Burgess Shale. It contains a growing collection of over 500 high resolution images representing 184 species in 135 genera. In addition, dozens of scientifically accurate drawings and breathtaking digital animations will allow you to visualize these organisms in three dimensions and see how they lived. ******* Anomalocaris - The largest predator of the Cambrian (3D Animation) ******* Virtual Sea Odyssey; Observe the creatures who lived in the Burgess Shale community from a "virtual submarine". - video ******* "Darwin's Dilemma examines some of the most important fossil discoveries ever made and with them, a mystery deeper than Charles Darwin ever imagined. For the fossil record of the Cambrian Explosion does not reveal the gradual development of life forms as Darwin posited in his work, but a period in which compound eyes, articulated limbs, sophisticated sensory organs and skeletal frames burst into existence seemingly out of nowhere." - Anika Smith - Discovery Institute One of the most enigmatic 'novelties' of the Cambrian explosion was the appearance of unique sexual reproduction for a wide variety of different species/phyla: How did the sexes originate? Why is it that the vast majority of living things require a "male and female" to reproduce? If evolution were true - doesn't it make much more sense that EVERY living organism was self-replicating and required no useless energy expenditure? When did the first male get here? When did the first female get here? How? Why? Wouldn't they have had to appear fully functional and at the same time in order for the next generation of organisms to arrive? Of course, they would. So, how is it that the first male and female for almost 2 million living organisms arrived together and fully functional so that reproduction could take place? "Sex is the QUEEN of evolutionary biology problems." Dr. Graham Bell - In his book, 'The Masterpiece of Nature' It is in the ancient seas of the Cambrian explosion, some 540 million years ago, where we find the abrupt appearance of many strangely diverse and complex forms of life. These complex life-forms appear suddenly with no evidence of transition from the bacteria and few other stable, and simple, life-forms that preceded them in the fossil record. These following quotes clearly illustrate this point. Materialistic Basis of the Cambrian Explosion is Elusive: BioEssays Vol. 31 (7):736 - 747 - July 2009 Excerpt: "going from an essentially static system billions of years in existence to the one we find today, a dynamic and awesomely complex system whose origin seems to defy explanation. Part of the intrigue with the Cambrian explosion is that numerous animal phyla with very distinct body plans arrive on the scene in a geological blink of the eye, with little or no warning of what is to come in rocks that predate this interval of time." ---"Thus, elucidating the materialistic basis of the Cambrian explosion has become more elusive, not less, the more we know about the event itself, and cannot be explained away by coupling extinction of intermediates with long stretches of geologic time, despite the contrary claims of some modern neo-Darwinists." *******www.evolutionnews****/2009/06/bioessays_article_admits_mater.html Does Lots of Sediment in the Ocean Solve the "Mystery" of the Cambrian Explosion? - Casey Luskin April, 2012 Excerpt: I think the Cambrian fossil record is surprisingly complete. I think it may be more complete than we realize. The reason for that is, for instance, if you look at the stratigraphy of the world, if I go and collect Cambrian rocks in Wales and find certain fossils, if I then go to China, I don't find the same species but I find the same sorts of fossils. If I go into Carboniferous rocks, I go to Canada, they are the same as what I find in this country. So there is a clear set of faunas and floras that take us through geological time. The overall framework is falling into position. - Simon Conway Morris *******www.evolutionnews****/2012/04/lots_of_sedimen059021.html Deepening Darwin's Dilemma - Jonathan Wells - Sept. 2009 Excerpt: "The truth is that (finding) “exceptionally preserved microbes” from the late Precambrian actually deepen Darwin’s dilemma, because they suggest that if there had been ancestors to the Cambrian phyla they would have been preserved." *******www.discovery****/a/12471 Deepening Darwin's Dilemma - Jonathan Wells - The Cambrian Explosion - video *******www.metacafe****/watch/4154263 Jonathan Wells - Cambrian Explosion - video ******* Recent experimental work has not been very cooperative to evolutionists, to put it mildly, in elucidating plausible evolutionary routes to multicellular organisms from single celled organisms: Brown Algae and The Serendipity of Multicellularity - Cornelius Hunter - June 2010 Excerpt: Instead of the expectation that multicellularity arose once and then proliferated, evolutionists now must say it arose independently several times. And instead of a sort of primitive multicellularity emerging and then undergoing evolutionary refinement, we must believe evolution first produced profoundly unlikely molecular machines, which then in turn enabled multicellularity. *******www.uncommondescent****/intelligent-design/brown-algae-and-the-serendipity-of-multicellularity/ Here are more articles on the suddenness of the Cambrian explosion: Evolution's Big Bang: “Yet, here is the real puzzle of the Cambrian Explosion for the theory of evolution. All the known phyla (large categories of biological classification), except one, first appear in the Cambrian period. There are no ancestors. There are no intermediates. Fossil experts used to think that the Cambrian lasted 75 million years.... Eventually the Cambrian was shortened to only 30 million years. If that wasn't bad enough, the time frame of the real work of bringing all these different creatures into existence was shortened to the first five to ten million years of the Cambrian. This is extraordinarily fast! Harvard's Stephen Jay Gould stated, "Fast is now a lot faster than we thought, and that is extraordinarily interesting." What an understatement! "Extraordinarily impossible" might be a better phrase! .... The differences between the creatures that suddenly appear in the Cambrian are enormous. In fact these differences are so large many of these animals are one of a kind. Nothing like them existed before and nothing like them has ever appeared again.” Dr. Raymond G. Bohlin, University of Illinois (B.S., zoology), North Texas State University (M.S., population genetics), University of Texas at Dallas (M.S., Ph.D., molecular biology). "Eyes and gills, jointed limbs and intestines, sponges and worms and insects and fish, all had appeared simultaneously. There had not been a gradual evolution of simple phyla such as sponges into the more complex phyla of worms and then on to other life forms such as insects. According to these fossils, at the most fundamental level of animal life, the phylum or basic body plan, the dogma of classical Darwinian evolution, that the simple had evolved into the more complex, that invertebrates had evolved into vertebrates over one hundred to two hundred million year was fantasy, not fact." Gerald L. Schroeder - The Science of God - Pg. 26 The unscientific hegemony of uniformitarianism - David Tyler - 2011 Excerpt: The summary of results for phyla is as follows. The pattern reinforces earlier research that concluded the Explosion is not an artefact of sampling. Much the same finding applies to the appearance of classes. *******www.arn****/blogs/index.php/literature/2011/05/16/the_unscientific_hegemony_of_uniformitar The mysterious Ediacara biota, which appeared abruptly, alongside the Sponges and Jellyfish, in the pre-Cambrian fossil record, and which defy classification as either plant or animal, much less classification of essential symbiotic purpose, largely disappeared from the fossil record a few million years before the Cambrian Explosion and thus are not seen to be viable as precursors to the Cambrian Explosion. Plant or Animal? Mysterious Fossils Defy Classification Excerpt: "Animals in the Ediacaran Period are almost universally bizarre, and it is very difficult to place them in any modern animal phyla," Xiao told LiveScience. *******www.livescience****/12883-plant-animal-mysterious-fossils-defy-classification.html The Avalon Explosion: Excerpt: Ediacara fossils [575 to 542 million years ago (Ma)] represent Earth's oldest known complex macroscopic life forms,,, A comprehensive quantitative analysis of these fossils indicates that the oldest Ediacara assemblage—the Avalon assemblage (575 to 565 Ma)—already encompassed the full range of Ediacara morphospace. (i.e. they appeared abruptly in the fossil record and retained their same basic shape and form throughout their tenure in the fossil record before they went extinct prior to the Cambrian explosion.) *******www.sciencemag****/cgi/content/abstract/319/5859/81 My hunch is that, as with photosynthetic bacteria, sulfate reducing bacteria, sponges, and jellyfish, Ediacara biota will ultimately be found to have a essential biogeochemical role in preparing the earth for more advanced life to appear in the Cambrian explosion. This following paper, although evolutionary in its basis, offers a few tantalizing clues as to what that essential purpose for Ediacara biota might have been. The mysterious Ediacara biota: Excerpt: "many questions remain. In particular, we might consider why the earliest known Ediacarans thrived in a deep ocean setting, when the oxygen apparently so vital for their evolution had already been abundant in shallow marine environments for millions of years." **********/publications/planetearth/2008/spring/spr08-animals.pdf This following study adds weight to my guess that the mysterious Ediacara biota were essential for detoxifying the deep ocean: You Mean There Really Was a Cambrian Explosion? - June 21 2010 Excerpt: Using novel geochemical techniques developed by Newcastle University’s Dr Simon Poulton, the team found that beneath oxygenated surface waters, mid-depth oceanic waters were rich in sulphide about 1.8 billion years ago, conditions that may have persisted until oxygenation of the deep ocean more than 1 billion years later. These widespread sulphidic conditions close to the continents, coupled with deeper waters that remained oxygen-free and iron-rich, would have placed major restrictions on both the timing and pace of biological evolution. Dr Poulton, who led the research, explained: “It has traditionally been assumed that the first rise in atmospheric oxygen eventually led to oxygenation of the deep ocean around 1.8 billion years ago. “This assumption has been called into question over recent years, and here we show that the ocean remained oxygen-free but became rich in toxic hydrogen-sulphide over an area that extended more than 100 km from the continents. It took a second major rise in atmospheric oxygen around 580 million years ago to oxygenate the deep ocean. *******www.uncommondescent****/intelligent-design/you-mean-there-really-was-a-cambrian-explosion/ Cambrian Explosion & Refutation Of Human Evolution *******lettherebelight-77.blogspot****/2010/08/corrected-link.html Background Music to video: Creation Calls -- are you listening? Music by Brian Doerksen ***********/watch?v=LwGvfdtI2c0
25 May 2012
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Entire video: Creation/Evolution: Natural Limits to Biological Change - Dr. Raymond G. Bohlin - video (presentation starts at the 13:00 minute mark of video) ***********/watch?v=Dk9wmQP7SdM&feature=bf_prev&list=SP9C519B84FE6C1202 With a Startling Candor, Oxford Scientist Admits a Gaping Hole in Evolutionary Theory - November 2011 Excerpt: As of now, we have no good theory of how to read [genetic] networks, how to model them mathematically or how one network meshes with another; worse, we have no obvious experimental lines of investigation for studying these areas. There is a great deal for systems biology to do in order to produce a full explanation of how genotypes generate phenotypes,,, *******www.evolutionnews****/2011/11/with_a_startling_candor_oxford052821.html The next evolutionary synthesis: Jonathan BL Bard (2011) Excerpt: We now know that there are at least 50 possible functions that DNA sequences can fulfill [8], that the networks for traits require many proteins and that they allow for considerable redundancy [9]. The reality is that the evolutionary synthesis says nothing about any of this; for all its claim of being grounded in DNA and mutation, it is actually a theory based on phenotypic traits. This is not to say that the evolutionary synthesis is wrong, but that it is inadequate – it is really only half a theory! *******www.biosignaling****/content/pdf/1478-811X-9-30.pdf New level of genetic diversity in human RNA sequences uncovered Excerpt: A detailed comparison of DNA and RNA in human cells has uncovered a surprising number of cases where the corresponding sequences are not, as has long been assumed, identical. The RNA-DNA differences generate proteins that do not precisely match the genes that encode them.,,, Nearly half of the RDDs uncovered in the new study cannot be explained by the activity of deaminase enzymes, however, indicating that unknown processes must be modifying the RNA sequence, either during or after transcription. ,,, Although all of the individuals analyzed in the study had a large number of RDDs, there was a great deal of variability in the specific RDDs found in each person's genetic material." *******www.physorg****/news/2011-05-genetic-diversity-human-rna-sequences.html The Fate of Darwinism: Evolution After the Modern Synthesis - David J. Depew and Bruce H. Weber - 2011 Excerpt: We trace the history of the Modern Evolutionary Synthesis, and of genetic Darwinism generally, with a view to showing why, even in its current versions, it can no longer serve as a general framework for evolutionary theory. The main reason is empirical. Genetical Darwinism cannot accommodate the role of development (and of genes in development) in many evolutionary processes.,,, *******www.springerlink****/content/845x02v03g3t7002/ Modern Synthesis of Neo-Darwinism Is Dead - No Evidence For Body Plan Morphogenesis From Embryonic Mutations - Paul Nelson - video *******www.metacafe****/watch/5548184/ In Embryo Development, Non-DNA Information Is at Least as Important as DNA - Jonathan Wells - May 2012 Excerpt: Evidence shows that non-DNA developmental information can be inherited in several ways. For example, it can be inherited through chromatin modifications, which affect gene expression without altering underlying DNA sequences. Another example is cytoplasmic inheritance, which involves cytoskeletal patterns and localization of intracellular molecules. Still another example is cortical inheritance, which involves membrane patterns. *******www.evolutionnews****/2012/05/in_embryo_devel060031.html “Live memory” of the cell, the other hereditary memory of living systems - 2005 Excerpt: To understand this notion of “live memory”, its role and interactions with DNA must be resituated; indeed, operational information belongs as much to the cell body and to its cytoplasmic regulatory protein components and other endogenous or exogenous ligands as it does to the DNA database. We will see in Section 2, using examples from recent experiments in biology, the principal roles of “live memory” in relation to the four aspects of cellular identity, memory of form, hereditary transmission and also working memory. ******* Poly-Functional Complexity equals Poly-Constrained Complexity ************/document/d/1xkW4C7uOE8s98tNx2mzMKmALeV8-348FZNnZmSWY5H8/edit Systems biology: Untangling the protein web - July 2009 Excerpt: Vidal thinks that technological improvements — especially in nanotechnology, to generate more data, and microscopy, to explore interaction inside cells, along with increased computer power — are required to push systems biology forward. "Combine all this and you can start to think that maybe some of the information flow can be captured," he says. But when it comes to figuring out the best way to explore information flow in cells, Tyers jokes that it is like comparing different degrees of infinity. "The interesting point coming out of all these studies is how complex these systems are — the different feedback loops and how they cross-regulate each other and adapt to perturbations are only just becoming apparent," he says. "The simple pathway models are a gross oversimplification of what is actually happening." *******www.nature****/nature/journal/v460/n7253/full/460415a.html Stephen Meyer - Functional Proteins And Information For Body Plans - video *******www.metacafe****/watch/4050681 Dr. Stephen Meyer comments at the end of the preceding video,,, ‘Now one more problem as far as the generation of information. It turns out that you don’t only need information to build genes and proteins, it turns out to build Body-Plans you need higher levels of information; Higher order assembly instructions. DNA codes for the building of proteins, but proteins must be arranged into distinctive circuitry to form distinctive cell types. Cell types have to be arranged into tissues. Tissues have to be arranged into organs. Organs and tissues must be specifically arranged to generate whole new Body-Plans, distinctive arrangements of those body parts. We now know that DNA alone is not responsible for those higher orders of organization. DNA codes for proteins, but by itself it does insure that proteins, cell types, tissues, organs, will all be arranged in the body. And what that means is that the Body-Plan morphogenesis, as it is called, depends upon information that is not encoded on DNA. Which means you can mutate DNA indefinitely. 80 million years, 100 million years, til the cows come home. It doesn’t matter, because in the best case you are just going to find a new protein some place out there in that vast combinatorial sequence space. You are not, by mutating DNA alone, going to generate higher order structures that are necessary to building a body plan. So what we can conclude from that is that the neo-Darwinian mechanism is grossly inadequate to explain the origin of information necessary to build new genes and proteins, and it is also grossly inadequate to explain the origination of novel biological form.’ - Stephen Meyer - (excerpt taken from Meyer/Sternberg vs. Shermer/Prothero debate - 2009) "Charles Darwin said (paraphrase), 'If anyone could find anything that could not be had through a number of slight, successive, modifications, my theory would absolutely break down.' Well that condition has been met time and time again. Basically every gene, every protein fold. There is nothing of significance that we can show that can be had in a gradualist way. It's a mirage. None of it happens that way. - Doug Axe PhD. Nothing In Molecular Biology Is Gradual - Doug Axe PhD. *******www.metacafe****/watch/5347797/ From Jerry Coyne, More Table-Pounding, Hand-Waving - May 2012 Excerpt: "More than 6 percent of genes found in humans simply aren't found in any form in chimpanzees. There are over fourteen hundred novel genes expressed in humans but not in chimps." Jerry Coyne - ardent and 'angry' neo-Darwinist - professor at the University of Chicago in the department of ecology and evolution for twenty years. He specializes in evolutionary genetics. *******www.evolutionnews****/2012/05/from_jerry_coyn060271.html Study Reports a Whopping "23% of Our Genome" Contradicts Standard Human-Ape Evolutionary Phylogeny - Casey Luskin - June 2011 Excerpt: For about 23% of our genome, we share no immediate genetic ancestry with our closest living relative, the chimpanzee. This encompasses genes and exons to the same extent as intergenic regions. We conclude that about 1/3 of our genes started to evolve as human-specific lineages before the differentiation of human, chimps, and gorillas took place. (of note; 1/3 of our genes is equal to about 7000 genes that we do not share with chimpanzees) *******www.evolutionnews****/2011/06/study_reports_a_whopping_23_of047041.html Could Chance Arrange the Code for (Just) One Gene? Excerpt: "our minds cannot grasp such an extremely small probability as that involved in the accidental arranging of even one gene (10^-236)." *******www.creationsafaris****/epoi_c10.htm Guy Walks Into a Bar and Thinks He's a Chimpanzee: The Unbearable Lightness of Chimp-Human Genome Similarity - Richard Sternberg - May 2009 *******www.evolutionnews****/2009/05/guy_walks_into_a_bar_and_think020401.html The Gorilla Who Broke the Tree - Doug Axe PhD. - March 2012 Excerpt: Well, the recent publication of the gorilla genome sequence shows that the expected pattern just isn’t there. Instead of a nested hierarchy of similarities, we see something more like a mosaic. According to a recent report [1], “In 30% of the genome, gorilla is closer to human or chimpanzee than the latter are to each other…” That’s sufficiently difficult to square with Darwin’s tree that it ought to bring the whole theory into question. And in an ideal world where Darwinism is examined the way scientific theories ought to be examined, I think it would. But in the real world things aren’t always so simple. *******www.biologicinstitute****/post/19703401390/the-gorilla-who-broke-the-tree Chimps are not like humans - May 2004 Excerpt: the International Chimpanzee Chromosome 22 Consortium reports that 83% of chimpanzee chromosome 22 proteins are different from their human counterparts,,, The results reported this week showed that "83% of the genes have changed between the human and the chimpanzee—only 17% are identical—so that means that the impression that comes from the 1.2% [sequence] difference is [misleading]. In the case of protein structures, it has a big effect," Sakaki said. ******* Chimp chromosome creates puzzles - 2004 Excerpt: However, the researchers were in for a surprise. Because chimps and humans appear broadly similar, some have assumed that most of the differences would occur in the large regions of DNA that do not appear to have any obvious function. But that was not the case. The researchers report in 'Nature' that many of the differences were within genes, the regions of DNA that code for proteins. 83% of the 231 genes compared had differences that affected the amino acid sequence of the protein they encoded. And 20% showed "significant structural changes". In addition, there were nearly 68,000 regions that were either extra or missing between the two sequences, accounting for around 5% of the chromosome.,,, "we have seen a much higher percentage of change than people speculated." The researchers also carried out some experiments to look at when and how strongly the genes are switched on. 20% of the genes showed significant differences in their pattern of activity. *******www.nature****/news/1998/040524/full/news040524-8.html Eighty percent of proteins are different between humans and chimpanzees; Gene; Volume 346, 14 February 2005: ******* Further notes: Falsification Of Neo-Darwinism by Quantum Entanglement/Information ************/document/d/1p8AQgqFqiRQwyaF8t1_CKTPQ9duN8FHU9-pV4oBDOVs/edit Let There Be Light - Intelligent Design - The Anthropic Hypothesis *******lettherebelight-77.blogspot****/2012/02/let-there-be-light.html
2 Jun 2012
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Entire video: Refuting Darwinian Evolution - Jon Rittenhouse - video ***********/watch?v=sLPk4IJw_E8 What evidence is found for the first life on earth? - article *******lettherebelight-77.blogspot****/2012/02/what-evidence-is-found-for-first-life.html Dean Kenyon, who was a leading Origin Of Life researcher as well as a college textbook author on the subject in the 1970s, admitted after years of extensive research: "We have not the slightest chance for the chemical evolutionary origin of even the simplest of cells". Origin Of Life? - Probability Of Protein And The Information Of DNA - Dean Kenyon - video ***********/watch?v=9VhR2BHhxeo Programming of Life - Probability of a Cell Evolving - video ***********/user/Programmingoflife#p/c/AFDF33F11E2FB840/9/nyTUSe99z6o Probability Of A Protein and First Living Cell - Chris Ashcraft - video (notes in description) *******vimeo****/31536455 The Origin of Life - Lecture On Probability - John Walton - Professor Of Chemistry - short video *******www.metacafe****/watch/4012749 Protein Molecules and "Simple" Cells - video ***********/watch?v=uFNwStNhHIc Evolution: Possible or Impossible? - free e-book (with plenty of examples from math) - by Dr. James F. Coppedge *******creationsafaris****/epoi_toc.htm Stephen Meyer - Proteins by Design - Doing The Math - video *******www.metacafe****/watch/6332250/ Centre for Intelligent Design Lecture 2011 by Stephen Meyer on 'Signature in the Cell' - video ***********/watch?v=NbluTDb1Nfs Signature in the Cell - Book Review - Ken Peterson Excerpt: If we assume some minimally complex cell requires 250 different proteins then the probability of this arrangement happening purely by chance is one in 10 to the 164th multiplied by itself 250 times or one in 10 to the 41,000th power. *******www.spectrummagazine****/reviews/book_reviews/2009/10/06/signature_cell In fact years ago Fred Hoyle arrived at approximately the same number, one chance in 10^40,000, for life spontaneously arising. From this number, Fred Hoyle compared the random emergence of the simplest bacterium on earth to the likelihood “a tornado sweeping through a junkyard might assemble a Boeing 747 therein”. Fred Hoyle also compared the chance of obtaining just one single functioning protein molecule, by chance combination of amino acids, to a solar system packed full of blind men solving Rubik’s Cube simultaneously. Professor Harold Morowitz shows the Origin of Life 'problem' escalates dramatically over the 1 in 10^40,000 figure when working from a thermodynamic perspective,: "The probability for the chance of formation of the smallest, simplest form of living organism known is 1 in 10^340,000,000. This number is 10 to the 340 millionth power! The size of this figure is truly staggering since there is only supposed to be approximately 10^80 (10 to the 80th power) electrons in the whole universe!" (Professor Harold Morowitz, Energy Flow In Biology pg. 99, Biophysicist of George Mason University) Dr. Don Johnson lays out some of the probabilities for life in this following video: Probabilities Of Life - Don Johnson PhD. - 38 minute mark of video a typical functional protein - 1 part in 10^175 the required enzymes for life - 1 part in 10^40,000 a living self replicating cell - 1 part in 10^340,000,000 *******www.vimeo****/11706014 Increasing Genomic Information - Don Johnson - video Excerpt: Forming the simplest life is 10^300,000,000 more likely that forming a human life ***********/watch?v=VYFq9mpCT6c Dr. Morowitz did another probability calculation working from the thermodynamic perspective with a already existing cell and came up with this number: DID LIFE START BY CHANCE? Excerpt: Molecular biophysicist, Horold Morowitz (Yale University), calculated the odds of life beginning under natural conditions (spontaneous generation). He calculated, if one were to take the simplest living cell and break every chemical bond within it, the odds that the cell would reassemble under ideal natural conditions (the best possible chemical environment) would be one chance in 10^100,000,000,000. You will have probably have trouble imagining a number so large, so Hugh Ross provides us with the following example. If all the matter in the Universe was converted into building blocks of life, and if assembly of these building blocks were attempted once a microsecond for the entire age of the universe. Then instead of the odds being 1 in 10^100,000,000,000, they would be 1 in 10^99,999,999,916 (also of note: 1 with 100 billion zeros following would fill approx. 20,000 encyclopedias) *******members.tripod****/~Black_J/chance.html Punctured cell will never reassemble - Jonathan Wells - 2:40 mark of video ***********/watch?v=WKoiivfe_mo The Humpty-Dumpty Effect: A Revolutionary Paper with Far-Reaching Implications - Paul Nelson - October 23, 2012 Excerpt: Tompa and Rose calculate the "total number of possible distinct patterns of interactions," using yeast, a unicellular eukaryote, as their model system; this "total number" is the size of the space that must be searched. With approximately 4,500 proteins in yeast, the interactome search space "is on the order of 10^7200, an unimaginably large number," they write -- but "more realistic" estimates, they continue, are "yet more complicated." Proteins present many possible surfaces for chemical interaction. "In all," argue Tompa and Rose, "an average protein would have approximately 3540 distinguishable interfaces," and if one uses this number for the interactome space calculation, the result is 10 followed by the exponent 7.9 x 10^10.,,, the numbers preclude formation of a functional interactome (of 'simple' life) by trial and error,, within any meaningful span of time. This numerical tantamount to a proof that the cell does not organize by random collisions of its interacting constituents. (i.e. that life did not arise, nor operate, by chance!) *******www.evolutionnews****/2012/10/a_revolutionary065521.html Also of interest is the information content that is derived in a cell when working from a thermodynamic perspective: “a one-celled bacterium, e. coli, is estimated to contain the equivalent of 100 million pages of Encyclopedia Britannica. Expressed in information in science jargon, this would be the same as 10^12 bits of information. In comparison, the total writings from classical Greek Civilization is only 10^9 bits, and the largest libraries in the world – The British Museum, Oxford Bodleian Library, New York Public Library, Harvard Widenier Library, and the Moscow Lenin Library – have about 10 million volumes or 10^12 bits.” – R. C. Wysong 'The information content of a simple cell has been estimated as around 10^12 bits, comparable to about a hundred million pages of the Encyclopedia Britannica." Carl Sagan, "Life" in Encyclopedia Britannica: Macropaedia (1974 ed.), pp. 893-894 of note: The 10^12 bits of information number for a bacterium is derived from entropic considerations, which is, due to the tightly integrated relationship between information and entropy, considered the most accurate measure of the transcendent quantum information/entanglement constraining a 'simple' life form to be so far out of thermodynamic equilibrium. "Is there a real connection between entropy in physics and the entropy of information? ....The equations of information theory and the second law are the same, suggesting that the idea of entropy is something fundamental..." Siegfried, Dallas Morning News, 5/14/90, [Quotes Robert W. Lucky, Ex. Director of Research, AT&T, Bell Laboratories & John A. Wheeler, of Princeton & Univ. of TX, Austin] For calculations, from the thermodynamic perspective, please see the following site: Moleular Biophysics – Information theory. Relation between information and entropy: - Setlow-Pollard, Ed. Addison Wesley Excerpt: Linschitz gave the figure 9.3 x 10^12 cal/deg or 9.3 x 10^12 x 4.2 joules/deg for the entropy of a bacterial cell. Using the relation H = S/(k In 2), we find that the information content is 4 x 10^12 bits. Morowitz' deduction from the work of Bayne-Jones and Rhees gives the lower value of 5.6 x 10^11 bits, which is still in the neighborhood of 10^12 bits. Thus two quite different approaches give rather concordant figures. ******* Ilya Prigogine was an eminent chemist and physicist who received two Nobel Prizes in chemistry. Regarding the probability of life originating by accident, he said: “The statistical probability that organic structures and the most precisely harmonized reactions that typify living organisms would be generated by accident, is zero.” Ilya Prigogine, Gregoire Nicolis, and Agnes Babloyantz, Physics Today 25, pp. 23-28. *******en.wikiquote****/wiki/Western_Thought_on_Creation Quotes of Note: The Theist holds the Intellectual High-Ground - March 2011 Excerpt: To get a range on the enormous challenges involved in bridging the gaping chasm between non-life and life, consider the following: “The difference between a mixture of simple chemicals and a bacterium, is much more profound than the gulf between a bacterium and an elephant.” (Dr. Robert Shapiro, Professor Emeritus of Chemistry, NYU) *******www.faithfulnews****/contents/view_content2/49631/rabbi-moshe-averick-the-theist-holds-the-intellectual-high-ground-apologetics-christian-apologetics-defending-gospel Scientists Prove Again that Life is the Result of Intelligent Design - Rabbi Moshe Averick - August 2011 Excerpt: “To go from bacterium to people is less of a step than to go from a mixture of amino acids to a bacterium.” - Dr. Lynn Margulis *******www.algemeiner****/2011/08/17/scientists-prove-again-that-life-is-the-result-of-intelligent-design/ Stephen Meyer - The Scientific Basis for the Intelligent Design Inference - video *******vimeo****/32148403
20 Jan 2013
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