Get the facts on Laser-Assisted In Situ Keratomileusis (LASIK) & Cataract with this 100%-accurate animated video. Part of Focus Apps' Understanding Disease: Ophthalmology series, the LASIK & Cataract app demonstrates computer-controlled laser surgery. LASIK is used to correct myopia, astigmatism, and hyperopia. Understand cataracts, a condition where a clouded eye lens impairs vision. This happens when the protein balance in the lens is upset. Explore the anatomy of the eye, eye function, refractory errors, correction with LASIK, cataract classification, symptoms, diagnosis, complications, surgery, and recovery.
Get the facts on Glaucoma with this 100%-accurate animated video. Part of Focus Apps' Understanding Disease: Ophthalmology series, the Glaucoma app explores the optical system and the various factors that lead to this condition. Glaucoma is a group of eye diseases caused by a buildup of intra-ocular pressure. Also understand the diagnostic and treatment options available
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LEVEL Study Published in British Journal of Ophthalmology Evaluates Macugen as Maintenance Treatment for Patients with Neovascular Age-Related Macular Degeneration
Palm Beach Gardens, FL - May 18, 2010 - Eyetech Inc. announced today that the British Journal of Ophthalmology (BJO) published online results from the LEVEL study evaluating MacugenTM (pegaptanib sodium) as a maintenance therapy in neovascular age-related macular degeneration (AMD). This large, open-label, uncontrolled, exploratory study enrolled 568 patients who had been treated one to three times for neovascular AMD, primarily with a non-selective VEGF-inhibitor such as ranibizumab or bevacizumab. During this induction phase, the mean visual acuity improved by 15.9 letters (49.6 letters to 65.5 letters). After entering the study, patients were switched to Macugen, a selective VEGF-inhibitor, with the possibility of using additional treatments if needed. At the end of this 54-week maintenance phase, mean final visual acuity was 61.8 letters. From the beginning of the induction phase to the end of maintenance phase, an approximately 16-month follow-up, 41 percent of patients gained at least 3 lines of visual acuity.
The study authors concluded that this induction-maintenance treatment strategy, using non-selective VEGF inhibitors then switching to Macugen, a selective VEGF inhibitor, may be an option for the long-term treatment of neovascular AMD. "A treatment protocol that combines the efficacy of a non-selective VEGF inhibitor with the safety profile of a selective VEGF inhibitor may be an attractive option, since elderly patients with AMD are already at increased risk of hypertension, stroke and other cardiovascular disease," said Thomas R. Friberg, M.D., lead investigator of the LEVEL study and Professor of Ophthalmology and Bio-Engineering at the University of Pittsburgh.
"This treatment approach may be of particular interest to retina specialists and their AMD patients with cardiovascular co-morbidities who require long-term treatment with anti-VEGF drugs to manage their neovascular AMD," continued Dr. Friberg. "Unlike non-selective VEGF inhibitors that should be administered monthly, Macugen is administered every six weeks. This substantially reduces the treatment burden on patients and their families."
Despite the limitations of an uncontrolled study, Macugen when used as a maintenance therapy showed adverse events rates similar to those observed in the pivotal Phase III V.I.S.I.O.N trial at one year. During one year of follow-up, there was no evidence of increased risk of endophthalmitis, retinal detachment of traumatic cataract. Most common ocular adverse events were punctate keratitis, eye pain and vitreous floaters. Reports of serious non-ocular, vascular events (including cardiovascular events) were rare.
About the LEVEL Study
LEVEL (EvaLuation of Efficacy and safety in maintaining Visual acuity with sEquential treatment of neovascuLar AMD) is a Phase IV, prospective, open-label, uncontrolled exploratory study designed to assess the efficacy of Macugen as a maintenance therapy in neovascular AMD patients who had at least one but not more than three prior treatments (induction phase) 30 to 120 days prior to study entry. Patients who showed significant clinical and/or anatomical improvement in their neovascular AMD, as determined by the study investigator, were enrolled in the LEVEL study and administered intravitreal injections of Macugen 0.3 mg every six weeks for 48 weeks with follow-up through week 54.
Additional treatments with other agents were allowed in the study eye at investigators' discretion for deteriorating AMD. Half of patients (283/568) required an additional treatment during the study, which was given approximately 5 months post-baseline on average. Of those who received an additional treatment, 46% required only one such treatment.
The results from the exploratory trial suggest that this induction/maintenance regimen may be a promising approach in the long-term treatment of ...
Ophthalmologist from the city of Hamden, CT, Dr. Jeffrey D. Gold speaks about ophthalmology practice and philosophy in this video interview. An ophthalmologist is doctor that deals with diseases of the eye. An ophthalmologist is a specialist in medical and surgical eye problems. Dr. Jeffrey D. Gold mentions that the roll an ophthalmologist is to treat eye diseases, and diagnose imperfections of the eye. However unlike optometrist an ophthalmologist is certified to perform surgery to correct imperfections of the eye. Dr. Jeffrey. D. Gold is also performs laser eye surgeries of all types. For more videos please visit the following site: *******www.youtube****/user/OphthalmologyHamden?feature=mhee
Dr. Jeffrey Gold, Ophthalmologist in Hamden CT, also serves the cities of: Hamden, North Haven, Bethany, Wallingford, Cheshire, New Haven, Woodbridge, Northford, and Prospect.
When you come into Medical Center Ophthalmology Associates, you'll finally get to see what you've been missing. In addition to vision exams and prescription glasses, we also treat most types of eye conditions and use FDA approved advanced laser technology. So contact our friendly and helpful office staff today to schedule your free consultation.
A new public survey released by the American Academy of Ophthalmology finds that few Americans believe they are at risk for eye disease. Yet more than half of all Americans will have some form of eye disease as they get older.
With diabetes rates continuing to rise in America, the American Academy of Ophthalmology is calling for screenings for diabetic retinopathy during Novemberâs Diabetic Eye Disease Awareness month.
What do a bungee cord, a pan of frying bacon and lawn-care chemicals have in common? They are just a few of the common items around the house that can cause eye injuries, which a new study from the American Academy of Ophthalmology (Academy) and the American Society of Ocular Trauma (ASOT) reports are increasingly occurring at home. The new Eye Injury Snapshot, a clinical survey of eye injuries across the U.S., found that nearly half of the 2.5 million eye injuries that Americans suffer annually now happen in and around the home in common places like the lawn, garden, kitchen or garage. For more information on this story and others, visit www.NewsInfusion****
Steven Rosenberg MD ..
Pediatric Ophthalmology ..
Medical School: Columbia University ..
Residency: Manhattan Eye and Ear ..
Fellowship: Scottish Rite Children's Medical Center
Learn about cataracts in dogs and cats. Dr. Douglas Esson, who is board certified in veterinary ophthalmology, talks about what a cataract is, what problems can be associated with them, and what treatment options are available. This information is not meant to replace the advice of your regular veterinarian.
www.nevyas**** - Nevyas Eye Associates is an ophthalmology office in Bala Cynwyd, PA. They also have offices throughout Philadelphia and in Marlton, NJ. Nevyas Eye Associates provides LASIK surgery, custom LASIK, bladeless LASIK, Chrystalens®, ICL and cataract and glaucoma treatment. If you are in the Pennsylvania, New Jersey or surrounding areas and would like more information about the laser and refractive surgery options available, please contact Dr. Herbert J. Nevyas by visiting www.nevyas****.
Patrick DeRespinis MD Pediatric Ophthalmology Residency: New Jersey Medical School
Fellowship:Manahattan Eye, Ear & Throat Hospital
Author of " Super Sight for Seymour Bright"
www.rochestereyecare.us – Dr. Mark Weingarten at Rochester Eye Care in Rochester, Michigan, is board certified in Ophthalmology and a certified laser eye surgeon. Dr. Weingarten performs routine eye care, as well as medical and surgical eye diseases. He also specializes in LASIK and cataract eye surgery. Visit his website at www.rochestereyecare.us today for more information about eye care, and to contact Dr. Weingarten.
Keith C. Charles, M.D.
Dr. Charles received his undergraduate degree from Duke University where he was elected to the Phi Beta Kappa honor society. He received his medical degree from the University of Southern California and completed a residency in Ophthalmology at Case Western Reserve University in Cleveland. His many accomplishments include a Fellowship in Cornea and Refractive Surgery at Emory University in Atlanta. Dr. Charles is board certified in Ophthalmology, a Clinical Professor at the University of Florida, and a certified international LASIK instructor.