First New Class of Topical Antibacterials in Nearly Two Decades
GlaxoSmithKline (NYSE: GSK) announced today that the U.S. Food and Drug Administration (FDA) has approved its antibacterial Altabax for the topical treatment of impetigo due to susceptible strains of Staphylococcus aureus or Streptococcus pyogenes, the two most common types of bacteria in this kind of infection.
Altabax represents the first new class of prescription topical antibacterials to be approved by the FDA in nearly two decades. Altabax is indicated for use twice daily for a five-day period in patients nine months of age and older. Other prescription topical antibacterials are used as much as three times daily for up to 12 days.
"The introduction of Altabax comes at a time when antibiotic resistance is at an increasingly high level," said Stan Block, MD, President, Kentucky Pediatric and Adult Research Inc. "Altabax provides clinicians with a convenient new means to effectively fight the bacteria that cause impetigo through an effect that is different from other antibiotics. In vitro, this new topical antibiotic has shown a low potential for the development of resistance, possibly because it works in a unique manner compared to other antibiotics."
Impetigo is a highly contagious infection of the top layers of the skin and is most common among infants and children ages 2 to 6 years. Children are especially susceptible to infections because their immune systems are still developing. Impetigo spreads easily in schools and child care settings, as well as anywhere groups of people are in close contact.
Condition affects 30 million Americans and costs $30 billion a year
April is irritable bowel syndrome (IBS) awareness month, a condition that causes Americans substantial pain, both physically and financially. The estimated 30 million Americans who suffer from IBS a disorder characterized by a range of symptoms, including abdominal pain and discomfort, bloating, constipation and diarrhea spend approximately $30 billion annually, excluding prescription and over the counter drug costs. It is the most common functional bowel disorder and is the second leading cause of work absenteeism in the United States.
To combat this disease, consumers are increasingly shopping for natural solutions in the form of probiotics, as a safe and cost-effective way of taking control of their digestive problems. Probiotics are beneficial bacteria that aid digestion, help strengthen the body's natural defenses and support a more appropriate balance of healthy bacteria in the gastrointestinal tract. However, probiotics are not all the same.
"Consumers need to know that not all probiotics are created equal," said Dr. Eamonn Quigley, Professor of Medicine and Human Physiology at the Cork University Hospital. "There are many probiotic strains on the market that are not clinically proven to have any benefits. The most important things to remember when shopping for a probiotic are to know what research lies behind the bacterial strain in the product and to be able identify the necessary information from the probiotic label."
Clinical data to support the benefits of a probiotic strain is essential when choosing a probiotic. Bifantis (Bifidobacterium infantis 35624) is the first and only probiotic that has been clinically proven to help manage the full range of symptoms of IBS in a large scale, placebo-controlled clinical trial. No other probiotic is backed by the clinical data supporting Bifantis. The clinical study was sponsored by P&G Health Sciences Institute.
This is what sent me to my first hospital trip in years, I'm that fat guy near the end. I had "Muscle Strain - extremity."
A little anti-climactic, but, damn, hospital bills are expensive
Phil Johnson, M.D. discusses why it's so important for HIV/AIDS patients to follow their antiretroviral (ARV) medication regimen as prescribed. During active infection, up to 10 billion HIV particles will be created each day. This provides ample chance for the virus to mutate in ways that provide resistance to the medication. By keeping the blood levels of the ARV medication high, that will keep the viral load low and reduce the opportunity for resistance mutations to flourish. When HIV develops resistance to one medication, it may develop resistance to other ones at the same time. Patients may also have to deal with side effects such as the redistribution of fat in the body and increases to their cholesterol level. Not every patient can tolerate every ARV. Therefore, it's critical for patients to make every ARV last as long as possible. When people with resistant HIV have unprotected sex, they may transmit resistant HIV to their sex partners, meaning the newly infected person will have far fewer treatment options. Genetic testing of the virus can be used to determine which medicaions the patient's particular strain(s) will be resistant to.
A viper 125mW laser pointer pops a balloon at 10 feet with out strain. Laser from www.dragonlasers.com
According to opponents of the U.S. immigration policy, the nation's population could surge anywhere from 100 to 200 million people by 2050. The U.S. Census also indicates immigration is the number one factor driving U.S. population growth, along with fertility (births). Under current policy, legal immigrants are allowed to sponsor relatives for admission, who in turn can sponsor their relatives in what has been termed "chain migration." Many opponents of the current policies believe Congress has not thoroughly studied the implications of massive population growth on this scale.
For example, labor experts believe the economic impact of a population boom on this scale would hit the lower income, working class the hardest by resulting in an over supply of low wage, low skilled workers. This could potentially drive down US working class wages and sometimes even displace US workers.
Many critics of current U.S. policy fear the greatest strain could be on the healthcare system. The Federation for American Immigration Reform estimates that half of all immigrants either don't have insurance or receive coverage at taxpayers' expense. And the Heritage Foundation estimates that the retirement costs of granting legal status to illegal immigrants would be $2.4 trillion dollars a year or more.
Produced for FAIR
An in-depth look into the strained back bone of Rock.
The Roadies can be seen training using The Octopus Tap: http://www.octopustap.com
Visit http://www.truenuff.com for higher quality videos, downloadable versions, RSS Feeds and our Podcast!
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It's easy for some of us to take water for granted. It's always available from our faucet and we have a wide selection of brands of bottled water to choose from in stores. But with continuing increases in the world's population, water resources are being strained as never before. It's a dwindling natural resource that is turning what should be a basic human right into a commodity to be bought and sold. These forces have threatened the well-being of poor communities across the globe.
Water pollution and water-related illnesses have also become world plagues.
On average, more people die each year from water borne diseases than from being killed in wars. It's clear we are standing on the brink of a global water crisis.
'Troubled Waters' will examine these issues through the eyes of people who are struggling with this crisis everyday in the United States and around the world. The documentary will also take a look at the theological side of water. Christians, Jews and Muslims all use water as a central theological element. Water is an important element in the ritualistic life of communities around the globe, intimately tied to its place in God's plan for humankind. International religious leaders express their concerns about the water crisis and what role they will play in preserving water, one of God's greatest gifts, for future generations.
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ING rates the Turkish Grand Prix at Istanbul Park highly among the Formula One circuits. These are the facts: Circuit- Istanbul Park is by far the best Grand Prix circuit built in recent years. The track flows constantly up- und downhill, and the curve combinations are amongst the most demanding in the Formula One. Strain on Drivers - Curve 8 puts over 5gs of centrifugal force on the drivers, taking them to their physical limits. The circuit is also hazardous, because cars tend to bottom out, lose grip and become instable. Vehicle Set Up - Beside the burning straightaways, there are also slow segments requiring exceptional traction. Good aerodynamic efficiency is the key to fast lap times. Engineering Requirements - With 66.5% full-throttle sections, Instanbul Park is among the fastest circuits. Drivers shift 38 times per lap, which is relatively easy on gearboxes. Brake wear is also comparatively low.
this guys just want show off.....
In materials science and metallurgy, toughness is the resistance to fracture of a material when stressed. It is defined as the amount of energy that a material can absorb before rupturing, and can be found by taking the area (i.e., by taking the integral) underneath the stress-strain curve.Pretending to be less intelligent than your prospect is a form of pretending to be stupid without irony that is exploited by salespeople. As in most fields, to be successful in sales requires a great deal of intelligence and empathy. However, if one is selling something, the prospective buyer must feel as though he is in control. Therefore, it can help to know how to pretend to be stupid. The most successful salespeople tend to be extremely intelligent despite their 'idiot facade', particularly when their prospect is of above average intelligence, or is himself trained in such sales techniques. The television character Lieutenant Columbo used this technique to solve crimes and is also known as Socratic irony.
The dog days of summer are here! And with them comes an increased use of air conditioners and an increased strain on our already aging power grid. The U.S. has nearly 500,000 miles of transmission lines carrying electricity to consumers. Many of them are more than 50 years old, a concern, as the “design-life” for many of the components – power transformers, circuit breakers, etc. is only 30 to 35 years on average.
So what’s being done to make sure the lights stay on? Experts say it’s a combination of building new power plants, improving older ones and using advanced transmission technologies. High voltage direct current (HVDC) technology, for example, allows communities to tap into electricity generated miles and miles away. Case in point – the new Neptune Regional Transmission System takes power generated in Sayreville, New Jersey, transports it underneath the Atlantic Ocean, and ultimately delvers it to a substation 65 miles away on Long Island, so it can be used by residents in more than half a million homes.
By taking electricity from sites with a large supply and delivering it efficiently and cheaply to areas with a large demand, experts say we can reduce the likelihood of blackouts. This is especially helpful, they say, in urban areas, which have growing populations and growing power use, but often lack the space needed to build new power plants.
Currently, more than a dozen HVDC projects exist in the U.S.
Produced for Siemens
How to open Coca-Cola (it is easy, not straining)!!!
Here's some more great techniques on how to massage the back. We're focusing on using the forearms here, so we can work more deeply as needed, without putting more strain on the hand. Go gently and feel your way!
Barley 1/4 cup
You pick of an orange, lemon or lime
What to do:
Add the barley to the pot and enough hot water to cover the barley. Boil the barley for 5 mins then strain. Discard the water as it will taste very bitter. Now boil the barley again for 15mins in approx 4 cups of hot water then strain. Add sugar to taste and if you like half of an orange, lemon or lime. Best served cold.
A mother-daughter relationship is strained when the teenage daughter chooses the wrong path
This is Not a Business Opportunity Video
Inspired by the "Wealth Theory" series of 'opportunity products.'
Set to the strains of 'I Want It All' by the fabulous Indie Pop Rock band "Future 86."
The tune was on its first album released almost three years ago and has found a home in Cable Television commercials in the Tri-State Area (NY, NJ, CT)
The Group was interviewed for Vegas Buzz News and Vegas Buzz Radio prior to the debut of its first album, in 2004.