I used lego mindstorms nxt to create a rubber band gun turret. I then used bluetooth to connect my wii-mote to my computer. I used a program called GlovePIE (can be downloaded here: )
GlovePIE interprets what buttons you press on the wii-mote and changes them into keyboard key presses or mouse clicks. I then used a program called OnBrick (can be downloaded here: ) which is a program that connects to your NXT and acts like a bluetooth controller. I set up hotkeys for different controls on OnBrick which are simulated by GlovePIE when I press buttons on my wii-mote which moves the motors on the nxt.