Evolution Vs. Functional Proteins - Where Did The Information Come From? - Doug Axe - Stephen Meyer

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Uploaded on January 13, 2010 by TheWordisalive

Design without a Designer? — December 9th, 2009 by Douglas Axe
Excerpt: For one protein subjected to this kind of experiment, the conclusion was that working sequences are as rare as one in a trillion trillion trillion trillion trillion trillion. In other words, they are unimaginably rare— far too rare to be stumbled upon by any unguided search, such as a Darwinian search.

Notice that this isn't a negative result in the sense of an unsuccessful attempt to measure something. The measurement was successful. Some will still see it as a negative result in that it precludes unguided searches. But since we do in fact encounter meaningful sentences every day, we know that intelligence is fully capable of producing what chance simply cannot produce. So we ought also to see this as a positive result— one that confirms the design explanation just as decisively as it refutes the Darwinian one.
http://biologicinstitute.org/2009/12/09/design-without-a-designer/

Eighty percent of proteins are different between humans and chimpanzees; Gene; Volume 346, 14 February 2005: http://www.ncbi.nlm.nih.gov/pubmed/15716009

John 1:1-3
In the beginning, the Word existed. The Word was with God, and the Word was God. He was with God in the beginning Through him all things were made; without him nothing was made that has been made.

(of note: "Word" in Greek is "Logos", and is the root word from which we get our word "Logic")

Darwin's Dilemma Trailer - Excellent Cambrian Explosion Movie Now Available On DVD - Sept. 2009
http://www.illustramedia.com/ddinfo.htm

Estimating the prevalence of protein sequences adopting functional enzyme folds: Doug Axe:
Excerpt: this implies the overall prevalence of sequences performing a specific function by any domain-sized fold may be as low as 1 in 10^77, adding to the body of evidence that functional folds require highly extraordinary sequences. (of note: the universe only has 10^80 sub-atomic particles)
http://www.ncbi.nlm.nih.gov/pubmed/15321723

A Man-Made ATP-Binding Protein Evolved Independent of Nature Causes Abnormal Growth in Bacterial Cells
Excerpt: "Recent advances in de novo protein evolution have made it possible to create synthetic proteins from unbiased libraries that fold into stable tertiary structures with predefined functions. However, it is not known whether such proteins will be functional when expressed inside living cells or how a host organism would respond to an encounter with a non-biological protein. Here, we examine the physiology and morphology of Escherichia coli cells engineered to express a synthetic ATP-binding protein evolved entirely from non-biological origins. We show that this man-made protein disrupts the normal energetic balance of the cell by altering the levels of intracellular ATP. This disruption cascades into a series of events that ultimately limit reproductive competency by inhibiting cell division."
http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0007385

Evolution vs ATP Synthase - Molecular Machine - video http://www.youtube.com/watch?v=qE3QJMI-ljc

Mutations are rare phenomena, and a simultaneous change of even two amino acid residues in one protein is totally unlikely. One could think, for instance, that by constantly changing amino acids one by one, it will eventually be possible to change the entire sequence substantially These minor changes, however, are bound to eventually result in a situation in which the enzyme has ceased to perform its previous function but has not yet begun its new duties. It is at this point it will be destroyed - along with the organism carrying it. Maxim D. Frank-Kamenetski, Unraveling DNA, 1997, p. 72. (Professor at Brown U. Center for Advanced Biotechnology and Biomedical Engineering)

The Ribosome, which makes the proteins, is found to be severely intolerant to any "random mutations".

The Ribosome: Perfectionist Protein-maker Trashes Errors
Excerpt: The enzyme machine that translates a cell's DNA code into the proteins of life is nothing if not an editorial perfectionist...the ribosome exerts far tighter quality control than anyone ever suspected over its precious protein products... To their further surprise, the ribosome lets go of error-laden proteins 10,000 times faster than it would normally release error-free proteins, a rate of destruction that Green says is "shocking" and reveals just how much of a stickler the ribosome is about high-fidelity protein synthesis.
http://www.sciencedaily.com/releases/2009/01/090107134529.htm

Intelligent Design - The Anthropic Hypothesis
http://lettherebelight-77.blogspot.com/

Tags:
Molecular Biology, Szostak, Axe, Evolution, Intelligent Design, Information, Jesus Is Lord, Darwin's Dilemma, Richard Dawkins, New Atheism, Stephen Meyer, Doug, Science & Tech
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