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During a routine desert patrol, an U.S. Military unit head by Captain Sturges (Brian Krause) is ambushed by insurgents. Just when they seemed to be outgunned, the attack suddenly stops...and their would-be assassins are dragged off by what a native liaison calls "the devils of the sand." Wounded in the battle, Sturges earns a ticket back home to the more hospitable deserts of the Southwestern United States.
Bringing back one of his fallen comrades, Sturges doesn't realize that a couple of camel spiders stowed away and now have access to an environment where they can breed at an exponential rate, freely hunting for prey and unafraid of any predator - including man. No place is safe, no one is beyond their paralyzing sting. In the end, a small band of hearty fighters are forced to make one last stand against the creatures.